Peer-reviewed research and study results in Anthroposophic Medicine
Safety, risks, side-effects and interactions of anthroposophic medicinal products (AMPs)
Oncology and mistletoe therapy
see also: www.mistelihoito.fi
and www.mistletoe.org
Clinical studies in different fields of medicine
Anthroposophic Medicine as integratiivinen medicine
External applications, nursing, massage
Basic and preclinical research
Further information/Databases/Links
Recent study results
Statement to an insufficient systematic review on Viscum album L. therapy. Matthes H, Thronicke A, Hofheinz RD, Baars EW, Martin DD, Martin D, Huber R, Breitkreuz T, Bar-Sela G, Galun D & Schad F. Evid Based Complement Alternat Med. eCAM 2020;2020:7091039. doi: 10.1155/2020/7091039
Impact of a Multimodal and Combination Therapy on Self-Regulation and Internal Coherence in German Breast Cancer Survivors With Chronic Cancer-Related Fatigue: A Mixed-Method Comprehensive Cohort Design Study. Mehl A, Reif M, Zerm R, Pranga D, Friemel D, Berger B, Brinkhaus B, Gutenbrunner C, Büssing A and Kröz M: Integr Cancer Ther 2020; 19:1534735420935618. doi: 10.1177/1534735420935618
The Anthroposophic Art Therapy Assessment Paint (AART-ASSESS-P): A peer-report instrument to assess patients' pictorial expression during Anthroposophic Painting Therapy.Mehl A, Brauer D, Didwiszus A, Gelin-Kröz B, Pranga D, Zerm R, Gutenbrunner C, Reif M and Kröz M: Explore (NY) 2020. doi: 10.1016/j.explore.2020.07.007
CAM treatments for cough and sore throat as part of an uncomplicated acute respiratory tract infection: a systematic review of prescription rates and a survey among European integrative medical practitioners. Baars EW, Belt-Van Zoen E, Willcox M,Huber R, Xiao-Yang Hu and van der Werf ET. European Journal of Integrative Medicine 2020;39: 101194, ISSN 18763820.
https://doi.org/10.1016/j.eujim.2020.101194
Impact of Oncological Therapy and Viscum album L Treatment on Cancer-Related Fatigue and Internal Coherence in Nonmetastasized Breast Cancer Patients. Oei SL, Thronicke A, Kröz, M, von Trott P, Schad F, Matthes, H. Integr Cancer Ther. 2020;19:1534735420917211. doi: 10.1177/1534735420917211
Evaluation of the effects of integrative non-pharmacological interventions on the internal coherence and resilience of breast cancer patients. Oei SL, Thronicke A, Matthes H & Schad F. [published online ahead of print, 2020 Jul 15]. Support Care Cancer. 2020;10.1007/s00520-020-05617-4. doi: 10.1007/s00520-020-05617-4
Overall Survival of Non-metastasized NSCLC Patients Treated With Add-On Viscum album L. Thronicke A, Matthes B, von Trott P, Schad F & Grah C. Integr Cancer Ther. 2020; doi: 10.1177/1534735420940384
Cost-effectiveness of real-world administration of chemotherapy and add-on Viscum album L. therapy compared to chemotherapy in the treatment of stage IV NSCLC patients. Thronicke A, Reinhold T, von Trott P, Grah C, Matthes B, Matthes H & Schad F. Plos ONE. 2020;15(7):e0236426. Published 2020 Jul 27. doi: 10.1371/journal.pone.0236426
Health-Related Quality of Life in Patients with Lung Cancer Applying Integrative Oncology Concepts in a Certified Cancer Centre. Thronicke A, von Trott P, Kröz M, Grah C, Matthes B & Schad F. Evid Based Complement Alternat Med. 2020;2020:5917382. Published 2020 May 10. doi: 10.1155/2020/5917382
Cost-Effectiveness of Real-World Administration of Concomitant Viscum album L. Therapy for the Treatment of Stage IV Pancreatic Cancer. Thronicke A, Reinhold T, von Trott P, Matthes H & Schad F. Evid Based Complement Alternat Med. 2020;2020:3543568. Published 2020 Mar 12. doi: 10.1155/2020/3543568
Mapping Physicians’ Experiences with Medicinal Products from Whole Medical Systems: A Descriptive Analysis of the Vademecum of Anthroposophic Medicines. Hamre HJ, Glockmann A, Marti J, Soldner G. Complement Med Res 2020. DOI: 10.1159/000507541 https://www.karger.com/Article/FullText/507541
Development of a Documentation Instrument for Movement-orientated Mind-Body-Therapies Taking the Example of Eurythmy-Therapy. Gerlach K, Rodrigues Recchia D, Büssing A. Complementary Therapies in Medicine 2019;44:91-93. DOI: https://doi.org/10.1016/j.ctim.2019.04.004
Reliability and First Validity of the Inner Correspondence Questionnaire for Painting Therapy (ICPTh) in a Sample of Breast Cancer Patients. Kröz M, Mehl A, Didwiszus A, Gelin-Kröz B, Reif M, Berger B, Ten Brink F, Zerm R, Girke M, Gutenbrunner C, Büssing A. Complementary Therapies in Medicine 2019;42(2):355-360. DOI: https://doi.org/10.1016/j.ctim.2018.12.002
The Contribution of Complementary and Alternative Medicine to Reduce Antibiotic Use: A Narrative Review of Health Concepts, Prevention, and Treatment Strategies. Baars EW, Belt-van Zoen E, Breitkreuz T, Martin D, Matthes H, von Schoen-Angerer T, Soldner G, Vagedes J, van Wietmarschen H, Patijn, O, Willcox M, von Flotow P, Teut M, von Ammon K, Thangavelu M, Wolf U, Hummelsberger J, Nicolai T, Hartemann P, Szöke H, McIntyre M, van der Werf E and Huber R. The Contribution of Complementary and Alternative Medicine to Reduce Antibiotic Use: A Narrative Review of Health Concepts, Prevention, and Treatment Strategies. Evidence-Based Complementary and Alternative Medicine Volume 2019, Article ID 5365608, 29 pages. doi.org/10.1155/2019/5365608. Full article: Open access
Effects of live music therapy on heart rate variability and selfreported stress and anxiety among hospitalized pregnant women: A randomized controlled trial. Teckenberg-Jansson P, Turunen S, Pölkki T, Lauri-Haikala M-J, Lipsanen J, Henelius A, Aitokallio-Tallberg A, Pakarinen S, Leinikka M and Huotilainen M. Nordic Journal of Music Therapy 2019, 28:1, 7-26. DOI: 10.1080/08098131.2018.1546223
Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronickea A, Li Oeia S, Merklea A Herbstreit C, Lemmens H-P, Grah C, Kröz M, Matthes H, Schad F. Complementary Therapies in Medicine, Volume 40, October 2018, Pages 145-150 https://doi.org/10.1016/j.ctim.2018.03.012 Open access
An assessment of the scientific status of anthroposophic medicine, applying criteria from the philosophy of science. Baars EW, Kiene H, Kienle GS, Heusser P, Hamre HJ. Complementary Therapies in Medicine Volume 40, October 2018, Pages 145-150 https://doi.org/10.1016/j.ctim.2018.04.010 Open access
Investigations on the constitutional types under consideration of anthropometric data, autonomic regulation and immunological parameters. Rentsch G, Steinborn C, Klemd AM, Kienle GS, Gründemann C, Huber R. . Complementary Therapies in Medicine 2018;40:133-144.
Long-term tumor-free survival in a metastatic pancreatic carcinoma patient with FOLFIRINOX/Mitomycin, high-dose, fever inducing Viscum album extracts and subsequent R0 resection: A case report. Werthmann PG, Inter P, Welsch T, Sturm A-K, Grützmann R, Debus M u. a. . Medicine. Dezember 2018;97(49):e13243. Full text
Intralesional and subcutaneous application of Viscum album L. (European mistletoe) extract in cervical carcinoma in situ. A CARE compliant case report.Reynel MB, Villegas Y, Kiene H, Werthmann PG, Kienle GS: Medicine: November 2018 - Volume 97 - Issue 48 - p e13420, doi: 10.1097/MD.0000000000013420. Full text
The management of chemical pleurodesis with Viscum album in patients with persistent air leakage. Park JB, Lee SA, Lee WS, Kim YH, Hwang JJ (2018) The management of chemical pleurodesis with Viscum album in patients with persistent air leakage. Journal of Thoracic Disease 10 (1), 371-376. Read more
The Subjective Dimension of Integrative Cancer Care: A Qualitative Study Exploring the Perspectives, Themes, and Observations of Experienced Doctors from the Area of Anthroposophic Medicine. Kienle GS, Mussler M, Fuchs D, Kiene H: Explore 2018; 14:342-351 Full text
Inverse relationship between reduced fatigue and severity of anemia in oncology patients treated with integrative medicine: understanding the paradox. Ben-Arye E, Dahan O, Shalom-Sharabi I, Samuels N (2018) Supportive Care in Cancer. 10 pp. DOI: 10.1007/s00520-018-4271-5
Speech-guided breathing retraining in asthma: a randomised controlled crossover trial in real-life outpatient settings. Von Bonin D, Klein SD, Würker, Streit E, Avianus O, Grah C, Salomon J and Wolf Ucorresponding author. BioMedCentral. Published online 2018 Jun 25. doi: 10.1186/s13063-018-2727-z. Open access
Overall survival of stage IV non-small cell lung cancer patients treated with Viscum album L. in addition to chemotherapy, a real-world observational multicenter analysis.Schad F, Thronick e A, Steele ML, Merkle A, Matthes B, Grah C, et al. (2018). PLoS ONE 13(8): e0203058. Open access
Clinical Safety of Combined Targeted and Viscum album L. Therapy in Oncological Patients. Thronicke A, Li Oei S, Merkle A, Matthes H, Schad, F (2018) Medicines 2018, 5, 100; doi:10.3390/medicines5030100. Open access
Complete Remission and Long-term Survival of a Patient with a Diffuse Large B-cell Lymphoma Under Viscum album Extracts After Resistance to R-CHOP: A Case Report. Gutsch J, Werthmann PG, Rosenwald A, Kienle GS: Anticancer Research. September 2018 vol. 38 no. 9 5363-5369. doi: 10.21873/anticanres.12865 Open access
On Caring and Sharing--Addressing Psychological, Biographical, and Spiritual Aspects in Integrative Cancer Care: A Qualitative Interview Study on Physicians’ Perspectives. Complementary Therapies in Medicine. Kienle GS, Mussler M, Fuchs D, Kiene H. May 2018. https://doi.org/10.1016/j.ctim.2018.04.012
Investigations on the constitutional types under consideration of anthropometric data, autonomic regulation and immunological parameters. Steinborn C, Rentsch G, Klemd AM, Kienle GS, Gründemann C. Complementary Therapies in Medicine, 2018 Volume 40, October 2018, Pages 133-144 Read more
An assessment of the scientific status of anthroposophic medicine, applying criteria from the philosophy of science. Baars EW Helmut Kiene H, Kienle GS, Heusser P, Hamre HJ. Complementary Therapies in Medicine. Volume 40, October 2018, Pages 145-150. Read more
Durable Clinical Remission of a Skull Metastasis Under Intralesional Viscum album Extract Therapy - A Case Report. Werthmann PG, Huber R, Kienle GS. Head & Neck 2018;00:1–5. Read more
A 21-year course of Merkel cell carcinoma with adjuvant Viscum album extract treatment: A case report. Werthmann PG, Kindermann L, Kienle GS. Complementary Therapies in Medicine. Volume 38, June 2018, Pages 58-60. Read more
Reduction of the frequency of recurrent diverticulitis episodes under treatment with the integrative medicine therapies Carpellum Mali comp. and Kalium aceticum comp. - A case report. Meyer R, Werthmann PG, Kienle GS. Complementary Therapies in Medicine. Volume 40, October 2018, Pages 203-206. Read more
Erfahrungen am Lebensende: Eine Umfrage bei Ärzten und Pflegenden eines Spitals für anthroposophisch erweiterte Medizin. Klein S, Kohler S, Krüerke D, Templeton A, Weibel A, Haraldsson E, Nahm M, Wolf U; Complementary Medicine Research 2018 25:38-43. https://doi.org/10.1159/000478090
A 4-year non-randomized comparative phase–IV study of early rheumatoid arthritis: integrative anthroposophic medicine for patients with preference against DMARDs versus conventional therapy including DMARDs for patients without preference. Hamre H J, Pham Van N, Kern Ch, Rau R, Klasen J, Schendel U, Gerlach L, Drabik A, Simon L; Patient Preference and Adherence 2018 12: 375-97 DOI: https://doi.org/10.2147/PPA.S145221
Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronicke A, Li Oei S, Merkle A, Herbstreit C, Lemmens HP, Grah C, Kröz M, Matthes H, Schad F; Complementary Therapies in Medicine 2018 DOI: https://doi.org/10.1159/000478655
Reviews
The Contribution of Complementary and Alternative Medicine to Reduce Antibiotic Use: A Narrative Review of Health Concepts, Prevention, and Treatment Strategies. Baars EW, Belt-van Zoen E, Breitkreuz T, Martin D, Matthes H, von Schoen-Angerer T, Soldner G, Vagedes J, van Wietmarschen H, Patijn, O, Willcox M, von Flotow P, Teut M, von Ammon K, Thangavelu M, Wolf U, Hummelsberger J, Nicolai T, Hartemann P, Szöke H, McIntyre M, van der Werf E and Huber R. The Contribution of Complementary and Alternative Medicine to Reduce Antibiotic Use: A Narrative Review of Health Concepts, Prevention, and Treatment Strategies. Evidence-Based Complementary and Alternative Medicine Volume 2019, Article ID 5365608, 29 pages. doi.org/10.1155/2019/5365608. Full article: Open access
A systematic literature review on the effectiveness of eurythmy therapy.
Lötzke D, Heusser P, Büssing A. J Integr Med. 2015 Jul;13(4):217-30. doi: 10.1016/S2095-4964(15)60163-7. http://www.ncbi.nlm.nih.gov/pubmed/25808905
Anthroposophic Medicine: An Integrative Medical System Originating in Europe. Kienle GS, Albonico H-U, Baars, Hamre HJ, Zimmermann P and Kiene H. Global Adv Health Med. 2013;2(6):20-31. DOI: 10.7453/gahmj.2012.087
Overview of the Publications From the Anthroposophic Medicine Outcomes Study (AMOS): A Whole System Evaluation Study. Hamre HJ, Kiene H, Ziegler R, Tröger W, Meinecke C, Schnürer C, Vögler H, Glockmann A, Kienle S: Global Adv Health Med. 2014;3(1):54-70. DOI: 10.7453/gahmj.2013.010.
Full article: http://www.gahmj.com/doi/pdf/10.7453/gahmj.2013.010
Arts Therapies for Anxiety, Depression, and Quality of Life in Breast Cancer Patients: A Systematic Review and Meta-Analysis. Boehm K, Cramer H, Staroszynski T and Ostermann T: Hindawi Publishing Corporation. Evidence-Based Complementary and Alternative Medicine.Volume 2014, Article ID 103297, 9 pages http://dx.doi.org/10.1155/2014/103297
Klinische Forschung zur Anthroposophischen Medizin – Update eines «Health Technology Assessment»-Berichts und Status Quo. Kienle GS, Glockmann A, Grugel R, Hamre HJ, Helmut Keine H: Forsch Komplementmed 2011;18:4-4 (DOI: 10.1159/000331812).
Influence of Viscum album L (European Mistletoe) Extracts on Quality of Life in Cancer Patients: A Systematic Review of Controlled Clinical Studies. Kienle GS and Kiene H. Integrative Cancer Therapies 2010:1-16.
Clinical research in anthroposophic medicine. Hamre HJ, Kiene H, Kienle GS. Altern Ther Health Med 2009;15(6):52-55.
Viscum album L. extracts in breast and gynaecological cancers: a systematic review of clinical and preclinical research. Kienle GS, Glockmann A, Schink M and Kiene H: Journal of Experimental & Clinical Cancer Research 2009;28:79.
Survival of cancer patients treated with mistletoe extract (Iscador): a systematic literature review. Ostermann T, Raak C, Büssing A BMC Cancer 2009, 9:451 (pp. 1-9) (http://www.biomedcentral.com/1471-2407/9/451) read more... Comment on Mistletoe therapy in oncology (Cochrane Review 2008) IFAEMM: Kiene, Kienle 2008 read more...
Complementary cancer therapy: a systematic review of prospective clinical trials on anthroposophic mistletoe extract. Kienle GS, Kiene H. Eur J Med Res 2007;12:103-19.
Anthroposophic Medicine, Effectiveness, utility, costs, safety. Kienle GS, Kiene H, Albonico HU. . Schattauer, Stuttgart, New York, 2006.
Mistletoe in cancer – a systematic review on controlled clinical trials. Kienle GS, Berrino F, Bussing A, Portalupi E, Rosenzweig S, Kiene H. Eur J Med Res 2003;8(3):109-19.
Safety, risks, side-effects and interactions of anthroposophic medicinal products AMPs
Clinical Safety of Combined Targeted and Viscum album L. Therapy in Oncological Patients. Thronicke A, Li Oei S, Merkle A, Matthes H, Schad, F (2018) Medicines 2018, 5, 100; doi:10.3390/medicines5030100. Open access
Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronickea A, Li Oeia S, Merklea A Herbstreit C, Lemmens H-P, Grah C, Kröz M, Matthes H, Schad F. Complementary Therapies in Medicine, Volume 40, October 2018, Pages 145-150 https://doi.org/10.1016/j.ctim.2018.03.012 Open access
Clinical safety of combined therapy of immune checkpoint inhibitors and Viscum album L. therapy in patients with advanced or metastatic cancer. Thronicke A, Steele ML, Grah C, Matthes B, Schad F (2017). BMC Complementary and Alternative Medicine 17:534. 10 pp. DOI: 10.1186/s12906-017-2045-0
Immune-related and adverse drug reactions to low versus high initial doses of Viscum album L. in cancer patients. Schad F, Thronicke A, Merkle A, Matthes H, Steele ML (2017). Phytomedicine 36, 54-58. DOI: 10.2016/j.phymed.2017.09.004
Safety of intravenously applied mistletoe extract – results from a phase I dose escalation study in patients with advanced cancer. Huber R, Schlodder D, Effertz C, Rieger S, Tröger W (2017). BMC Complementary and Alternative Medicine 17:465. 8 pp. DOI: 10.1185/s12906-017-1971-1
Effects of mistletoe products on pharmacokinetic drug turnover by inhibition and induction of cytochrome P450 activities. Schink M, Dehus O (2017). BMC Complemetary and Alternative Medicine 17:521. 8 pp. DOI: 10.1186/s12096-017-2028-1
Use and Safety of Intratumoral Application of European Mistletoe (Viscum album L) Preparations in Oncology. Steele ML, Axtner J, Happe A, Kröz, M, Matthes, H and Schad F. Integr Cancer Ther March 2015 vol. 14 no. 2 140-148. DOI: 10.1177/1534735414563977 ict.sagepub.com.
Safety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study. Steele ML, Axtner J, Happe A, Kröz, Matthes and Schad F. Evidence-Based Complementary and Alternative Medicine, 2014; Article ID 236310. Volume 2014,http://dx.doi.org/10.1155/2014/236310
Interaction of standardized mistletoe (Viscum album) extracts with chemotherapeutic drugs regarding cytostatic and cytotoxic effects in vitro. Weissenstein U , Kunz M , Urech K and Baumgartner S. BMC Complementary and Alternative Medicine 2014, 14 :6 Open access: http://www.biomedcentral.com/1472-6882/14/6
Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients. Steele ML, Axtner J, Happe A, Kröz M, Matthes H and Schad F. Evidence-Based Complementary and Alternative Medicine Volume 2014, Article ID 724258, 11 pages http://dx.doi.org/10.1155/2014/724258
Quality of life of patients with advanced pancreatic cancer during treatment with mistletoe: a randomized controlled trial. Tröger, W.; Galun, D.; Reif, M.; Schumann, A.; Stanković, N.; Milićević, M. 2014. Quality of life of patients with advanced pancreatic cancer during treatment with mistletoe: a randomized controlled trial. Dtsch Ärztebl Int 111(29–30): 493–502. doi:10.3238/arztebl.2014.0493. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150026/; http://www.aerzteblatt.de/pdf.asp?id=161151
Additional therapy with a mistletoe product during adjuvant chemotherapy of breast cancer patients improves quality of life. Tröger, W.; Ždrale, Z.; Tišma, N.; Matijašević, M. 2014. Additional Therapy with a Mistletoe Product during Adjuvant Chemotherapy of Breast Cancer Patients Improves Quality of Life: An Open Randomized Clinical Pilot Trial. Evid Based Complement Alternat Med 2014: 430518. doi:10.1155/2014/430518. https://www.hindawi.com/journals/ecam/2014/430518/
Viscum [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: a randomised clinical trial on overall survival. Tröger, W.; Galun, D.; Reif, M.; Schumann, A.; Stanković, N.; Milićević, M. 2013. Viscum album [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: a randomized clinical trial on overall survival. Eur. J. Cancer 49(18): 3788–3797. https://www.ncbi.nlm.nih.gov/pubmed/23890767; http://www.ejcancer.com/article/S0959-8049%2813%2900550-9/pdf
NCCAM/NCI Phase 1 Study of Mistletoe Extract and Gemcitabine in Patients with Advanced Solid Tumors. Mansky PJ, Wallerstedt DB, Sannes TS, Stagl J, Johnson LL, Blackman MR, Grem JL, Swain SM, Monahan BP: Evidence-Based Complementary and Alternative Medicine 2013, 2013: 964592 http://www.hindawi.com/journals/ecam/2013/964592/
Network Oncology (NO) – a Clinical Cancer Register for Health Services Research and the Evaluation of Integrative Therapeutic Interventions in Anthroposophic Medicine. Schad F, Axtner J, Happe A, Breitkreuz T, Paxino C, Gutsch J, Matthes B, Debus M, Kröz M, Spahn G, Riess H, von Laue H and Matthes H. Forsch Komplementmed 2013;20:353–360 Published online: October 24, 2013 DOI: 10.1159/000356204 Accessible online at: www.karger.com/fok
Five-year follow-up of patients with early stage breast cancer after a randomized study comparing additional treatment with a mistletoe extract to chemotherapy alone. Tröger, W.; Ždrale, Z.; Stanković, N.; Matijašević, M. 2012. Fiveyear follow-up of patients with early stage breast cancer after a randomized study comparing additional treatment with viscum album (L.) extract to chemotherapy alone. Breast Cancer (Auckl) 6: 173–180. doi:10.4137/BCBCR.S10558. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493140/
Anthroposophic medicine in pediatric primary care: a prospective, multicenter observational study on prescribing patterns. Jeschke E, Ostermann T, Tabali M, Kroz M, Bockelbrink A, Witt CM, Willich SN, Matthes H: Altern Ther Health Med 2011;17:18-28.
Pharmacotherapy of elderly patients in everyday anthroposophic medical practice: a prospective, multicenter observational study. Jeschke E, Ostermann T, Vollmar HC, Tabali M, Kröz M, Bockelbrink A, Witt CM, Willich SN, Matthes H. BMC Geriatrics 2010, 10:48. read more
The treatment of children with anthroposophic medicine in daily primary care - Results of a network study. Jeschke E, Ostermann T, Tabali M, Bockelbrink A, Witt C, Willich S, Matthes H. European Journal of Integrative Medicine 2009;1(4):203. read more
Prescribing practices in the treatment of upper respiratory tract infections in anthroposophic medicine. Jeschke E, Lueke C, Ostermann T, Tabali M, Huebner J, Matthes H. Forsch Komplementärmed 2007;14:207-15.
QuaDoSta - ein frei konfigurierbares System zur Unterstützung multizentrischer Datenerhebungen in medizinischer Versorgung und Forschung. Jeschke E, Schad F, Pissarek J, Matthes B, Albrecht U, Matthes H. GMS Med Inform Biom Epidemiol 2007;3(2):Doc 10.
Quality of life is improved in breast cancer patients by Standardised Mistletoe Extract PS76A2 during chemotherapy and follow-up: a randomised, placebo-controlled, double-blind, multicentre clinical trial. Semiglasov VF, Stepula VV, Dudov A, Schnitker J, Mengs U: Anticancer Res 2006, 26:1519-1530 http://ar.iiarjournals.org/content/26/2B/1519.full.pdf
Safety of homeopathic injectables for subcutaneous administration: a documentation of the experience of prescribing practitioners.Baars EW, Adriaansen-Tennekes R, Eikmans KJ. J Altern Complement Med 2005;11(4):609-616.
Impact of complementary mistletoe extract treatment on quality of life in breast, ovarian and non-small cell lung cancer patients. A prospective randomized controlled clinical trial. Piao BK, Wang YX, Xie GR, Mansmann U, Matthes H, Beuth J, Lin HS: Anticancer Res 2004, 24:303-309 http://ar.iiarjournals.org/content/24/1/303.full.pdf
Clinical studies in different fields of medicine
Allergic disease and sensitization in Steiner school children. Floistrup H, et al. The Parsifal Study Group. J Allergy Clin Immunol. 2006 Jan;117(1):59-66. Epub 2005 Nov 28.
Atopy in children of families with an anthroposophic lifestyle. Alm JS, Swartz J, Lilja G, Scheynius A, Pershagen G. Lancet. 1999 May 1;353(9163):1485-8. (1999)
Allergic disease and sensitization in Steiner school children. Floistrup H, Swartz J, Bergstrom A, Alm JS, Scheynius A, van Hage M, Waser M, Braun-Fahrlander C, Schram-Bijkerk D, Huber M, et al. J Allergy Clin Immunol 2006;117(1):59-66.
Bacterial and fungal agents in house dust and wheeze in children: the PARSIFAL study. Schram-Bijkerk D, Doekes G, Douwes J, Boeve M, Riedler J, Ublagger E, von Mutius E, Benz MR, Pershagen G, van Hage M, et al. Clin Exp Allergy 2005;35(10):1272-1278.
Bacterial and fungal components in house dust of farm children, Rudolf Steiner school children and reference children--the PARSIFAL Study.Schram D, Doekes G, Boeve M, Douwes J, Riedler J, Ublagger E, von Mutius E, Budde J, Pershagen G, Nyberg F, et al. Allergy 2005;60(5):611-618.
An anthroposophic lifestyle and intestinal microflora in infancy. Alm JS, Swartz J, Bjorksten B, Engstrand L, Engstrom J, Kuhn I, Lilja G, Mollby R, Norin, E, Pershagen G, Reinders C, Wreiber K, Scheynius A . Pediatr Allergy Immunol 2002;13(6) :402-11.
Training effect of eurythmy therapy on specific oscillations of heart rate variability.
Edelhäuser, F.; Minnerop, A.; Trapp, B.; Büssing, A.; Cysarz, D. 2015. Eurythmy therapy increases specific oscillations of heart rate variability. BMC Complement Altern Med 2015: 167. doi:10.1186/s12906-015-0684-6. http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0684-6
Eurythmy therapy increases specific oscillations of heart rate variability. Edelhäuser F, Antje Minnerop A, Trapp B, Büssing A 3 and Cysarz D. BMC Complementary and Alternative Medicine (2015) 15:167 DOI 10.1186/s12906-015-0684-6. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457978/
Anwendung von Cardiodoron® bei Patienten mit funktionellen Herz-Kreislauf-Beschwerden und/oder Schlafstörungen – Ergebnisse einer prospektiven, nichtinterventionellen Beobachtungsstudie. Claudia Rother,C. Forsch Komplementmed 2013;20:334–344 Published online: October 21, 2013 DOI: 10.1159/000355255
Effect of Colchicum autumnale in patients with goitre and euthyroidism or mild hyperthyroidism.
Scheffer, C.; Debus, M.; Heckmann, C.; Cysarz, D.; Girke, M. 2016. Colchicum autumnale in Patients with Goitre with Euthyroidism or Mild Hyperthyroidism: Indications for a Therapeutic Regulative Effect – Results of an Observational Study. Evid Based Complement Alternat Med 2016: 2541912. doi:10.1155/2016/2541912. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756131/
Improvement of Asthma and Gastroesophageal Reflux Disease With Oral Pulvis stomachicus cum Belladonna, a Combination of Matricaria recutita, Atropa belladonna, Bismuth, and Antimonite: A Pediatric Case Report. von Schoen-Angerer T, Madeleyn R, Kiene H, Kienle GS, Vagedes J. 2015 http://www.gahmj.com/doi/full/10.7453/gahmj.2015.019
Patient-centered outcomes on quality of life and Anthroposophic healthcare: a qualitative triangulation study. Koster EB, Baars EW and Delnoij DMJ. Qual Life Res. 2016. DOI 10.1007/s11136-016-1276-8 http://link.springer.com/article/10.1007/s11136-016-1276-8
Influence of spirituality on cool down reactions, work engagement, and life satisfaction in anthroposophic health care professionals. Büssing A, Lötzke D, Glöckler M, Heusser P. 2015. Influence of spirituality on cool down reactions, work engagement, and life satisfaction in anthroposophic health care professionals. Evid Based Complement Alternat Med. doi: 10.1155/2015/754814. https://www.hindawi.com/journals/ecam/2015/754814/
Patients whose GP knows complementary medicine tend to have lower costs and live longer. Peter Kooreman P and Baars EW (2010): Eur J Health Econ DOI 10.1007/s10198-011-0330-2
Sleep quality in pregnancy during treatment with Bryophyllum pinnatum: An observational study. Lambrigger-Steiner C, Simões-Wüst AP, Kuck A, Fürer K, Hamburgere M and von Mandach U. Phytomedicine 2014; 21: 753–757. http://dx.doi.org/10.1016/j.phymed.2013.11.003
Improvement of sleep quality during treatment with Bryophyllum. Simoes-Wüst, A.P.; Hassani, T.A.; Müller-Hübenthal, B.; Pittl, S.; Kuck, A.; Meden, H.; Eberhard, J.; Decker, M.; Fürer, K.; von Mandach, U.; Bryophyllum Collaborative Group. 2015. Sleep Quality Improves During Treatment with Bryophyllum pinnatum: An Observational Study on Cancer Patients. Integr Cancer Ther 2015; 14(5): 452–459. doi:10.1177/1534735415580680. https://www.ncbi.nlm.nih.gov/pubmed/25873294
Anthroposophic therapies in chronic disease: the Anthroposophic Medicine Outcomes Study (AMOS) Hamre HJ, Becker-Witt C, Glockmann A, Ziegler R, Willich SN, Kiene H. Eur J Med Res. 2004 Jul 30;9(7):351-60. read more.
Anthroposophic therapy for children with chronic disease: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Meinecke C, Glockmann A, Willich SN, Kiene H. BMC Pediatr 2009;9:39 read more
Predictors of outcome after 6 and 12 months following anthroposophic therapy for adult outpatients with chronic disease: a secondary analysis from a prospective observational study. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Willich SN, Kiene H. BMC Research Notes 2010 Aug 3;3(218). read more
Long-term outcomes of anthroposophic therapy for chronic low back pain: A two-year follow-up analysis. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Ziegler R, Willich SN, Kiene H. Journal of Pain Research 2009;2:75-85. read more
Outcome of anthroposophic medication therapy in chronic disease: A 12-month prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Kienle GS, Willich SN, et al. Drug Design, Development and Therapy 2008;2:25-37.
Anthroposophic vs. conventional therapy for chronic low back pain: a prospective comparative study. Hamre H, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Eur J Med Res 2007;12:302-10.
Anthroposophic medical therapy in chronic disease: a four-year prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. BMC Complement Altern Med 2007;7(10):DOI 10.1186/1472-6882-7-10.
Anthroposophic therapy for attention deficit hyperactivity: a two-year prospective study in outpatients. Harald J Hamre, Claudia M Witt, Gunver S Kienle, Christoph Meinecke, Anja Glockmann, Renatus Ziegler, Stefan N Willich, Helmut Kiene. International Journal of General Medicine 2010:3 239–253.
Anthroposophy and Integrative Care at the End of Life. Ciro Augusto Floriani CA. Alternative and complementary therapies. 2016; 22(3): DOI: 10.1089/act.2016.29055.caf http://online.liebertpub.com/doi/abs/10.1089/act.2016.29055.caf
Usage of Complementary and Alternative Medicine Interventions by German Older Adults. Büssing A, Ostermann T, Heusser P, Matthiessen PF: J Altern Complement Med. 2011; 17(6):487-489
Pharmacotherapy of elderly patients in everyday anthroposophic medical practice: a prospective, multicenter observational study. Jeschke E, Ostermann T, Vollmar HC, Tabali M, Kröz M, Bockelbrink A, Witt CM, Willich SN, Matthes H. BMC Geriatrics 2010, 10:48. read more...
The self regulation questionnaire as a measure in quality of life research.Büssing A, Girke M, Heckmann C, Matthiesen P, Schad F, Ostermann T, Kröz M. Eur J Med Res 2009, 14(5):223-227. read more...
Health Care and Health Policies
Patient-centered outcomes on quality of life and Anthroposophic healthcare: a qualitative triangulation study. Koster EB, Baars EW and Delnoij DMJ. Qual Life Res. 2016. DOI 10.1007/s11136-016-1276-8 http://link.springer.com/article/10.1007/s11136-016-1276-8
Health services research of integrative oncology in palliative care of patients with advanced pancreatic cancer. Axtner J , Steele M, Kröz M, Spahn G, Matthes H and Schad F. BMC Cancer (2016) 16:579 DOI 10.1186/s12885-016-2594-5. https://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2594-5
Opposite Drug Prescription and Cost Trajectories following Integrative and Conventional Care for Pain – A Case-Control Study. Sundberg, Petzold M, Kohls N and Falkenberg T. PLoS ONE 2014; 9(5): e96717. doi:10.1371/journal.pone.0096717.
Integrative versus Conventional Therapy of Chronic Otitis Media with Effusion and Adenoid Hypertrophyin Children: A Prospective Observational Study. Szoeke H, Maródi M, Sallay Z, Székely B, Sterner MG and Hegyi G.: Forsch Komplementmed 2016;23:231–239. DOI: 10.1159/000448440. http://www.karger.com/Article/PDF/448440
Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions. Hamre HJ, Glockmann A, Schwarz R, Riley DS, Baars EW, Kiene H and Kienle GS. Evidence-Based Complementary and Alternative Medicine Volume 2014 (2014), Article ID 243801, 17 pages Full article open access: http://dx.doi.org/10.1155/2014/243801
Use and safety of anthroposophic medications for acute respiratory and ear infections: a prospective cohort study. Hamre HJ, Glockmann A, Fischer M, Riley D, Baars E, Kiene H. . Drug Target Insights 2007;2:209-19.
Effect of Colchicum autumnale in patients with goitre and euthyroidism or mild hyperthyroidism.
Scheffer, C.; Debus, M.; Heckmann, C.; Cysarz, D.; Girke, M. 2016. Colchicum autumnale in Patients with Goitre with Euthyroidism or Mild Hyperthyroidism: Indications for a Therapeutic Regulative Effect – Results of an Observational Study. Evid Based Complement Alternat Med 2016: 2541912. doi:10.1155/2016/2541912. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756131/
Sleep quality in pregnancy during treatment with Bryophyllum pinnatum: An observational study. Lambrigger-Steiner C, Simões-Wüst AP, Kuck A, Fürer K, Hamburgere M and von Mandach U. Phytomedicine 2014; 21: 753–757. http://dx.doi.org/10.1016/j.phymed.2013.11.003
Improvement of sleep quality during treatment with Bryophyllum. Simoes-Wüst, A.P.; Hassani, T.A.; Müller-Hübenthal, B.; Pittl, S.; Kuck, A.; Meden, H.; Eberhard, J.; Decker, M.; Fürer, K.; von Mandach, U.; Bryophyllum Collaborative Group. 2015. Sleep Quality Improves During Treatment with Bryophyllum pinnatum: An Observational Study on Cancer Patients. Integr Cancer Ther 2015; 14(5): 452–459. doi:10.1177/1534735415580680. https://www.ncbi.nlm.nih.gov/pubmed/25873294
Anthroposophic Therapy for Migraine: A Two-Year Prospective Cohort Study in Routine Outpatient Settings. Harald J. Hamre, Claudia M. Witt, Gunver S. Kienle, Anja Glockmann, Renatus Ziegler, Andreas Rivoir, Stefan N. Willich and Helmut Kiene. The Open Neurology Journal, 2010; Volume 4:100-110. Open access
Spiritual needs of mothers with sick new born or premature infants– A cross sectional survey among German mothers. Büssing A, Waßermann U, Hvidt N Ch, Längler A, Thiel M; Australian College of Midwives 2017 DOI: https://doi.org/10.1016/j.wombi.2017.08.002
Sleep quality in pregnancy during treatment with Bryophyllum pinnatum: An observational study. Lambrigger-Steiner C, Simões-Wüst AP, Kuck A, Fürer K, Hamburgere M and von Mandach U. Phytomedicine 2014; 21: 753–757. http://dx.doi.org/10.1016/j.phymed.2013.11.003
Effect of Bryophyllum pinnatum versus fenoterol on uterine contractility. Gwehenberger B, Rist L, Huch R, von Mandach U: Eur J Obstet Gynecol Reprod Biol 2004; 113(2):164-71.
Oncology and mistletoe treatment
A 4-year non-randomized comparative phase–IV study of early rheumatoid arthritis: integrative anthroposophic medicine for patients with preference against DMARDs versus conventional therapy including DMARDs for patients without preference. Hamre H J, Pham Van N, Kern Ch, Rau R, Klasen J, Schendel U, Gerlach L, Drabik A, Simon L; Patient Preference and Adherence 2018 12: 375-97 DOI: https://doi.org/10.2147/PPA.S145221
Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronicke A, Li Oei S, Merkle A, Herbstreit C, Lemmens HP, Grah C, Kröz M, Matthes H, Schad F; Complementary Therapies in Medicine 2018 DOI: https://doi.org/10.1159/000478655
Durable Clinical Remission of a Skull Metastasis Under Intralesional Viscum album Extract Therapy - A Case Report. Werthmann PG, Huber R, Kienle GS. Head & Neck 2018;00:1–5. Read more
A 21-year course of Merkel cell carcinoma with adjuvant Viscum album extract treatment: A case report. Werthmann PG, Kindermann L, Kienle GS. Complementary Therapies in Medicine. Volume 38, June 2018, Pages 58-60. Read more
Overall survival of stage IV non-small cell lung cancer patients treated with Viscum album L. in addition to chemotherapy, a real-world observational multicenter analysis. Schad F, Thronick e A, Steele ML, Merkle A, Matthes B, Grah C, et al. (2018). PLoS ONE 13(8): e0203058. Open access
Clinical Safety of Combined Targeted and Viscum album L. Therapy in Oncological Patients. Thronicke A, Li Oei S, Merkle A, Matthes H, Schad, F (2018) Medicines 2018, 5, 100; doi:10.3390/medicines5030100. Open access
Complete Remission and Long-term Survival of a Patient with a Diffuse Large B-cell Lymphoma Under Viscum album Extracts After Resistance to R-CHOP: A Case Report. Gutsch J, Werthmann PG, Rosenwald A, Kienle GS: Anticancer Research. September 2018 vol. 38 no. 9 5363-5369. doi: 10.21873/anticanres.12865 Open access
Long-term tumor-free survival in a metastatic pancreatic carcinoma patient with FOLFIRINOX/Mitomycin, high-dose, fever inducing Viscum album extracts and subsequent R0 resection: A case report. Werthmann PG, Inter P, Welsch T, Sturm A-K, Grützmann R, Debus M u. a. . Medicine. Dezember 2018;97(49):e13243. Full text
Intralesional and subcutaneous application of Viscum album L. (European mistletoe) extract in cervical carcinoma in situ. A CARE compliant case report.Reynel MB, Villegas Y, Kiene H, Werthmann PG, Kienle GS: Medicine: November 2018 - Volume 97 - Issue 48 - p e13420, doi: 10.1097/MD.0000000000013420. Full text
Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronickea A, Li Oeia S, Merklea A Herbstreit C, Lemmens H-P, Grah C, Kröz M, Matthes H, Schad F. Complementary Therapies in Medicine, Volume 40, October 2018, Pages 145-150 https://doi.org/10.1016/j.ctim.2018.03.012 Open access
Clinical safety of combined therapy of immune checkpoint inhibitors and Viscum album L. therapy in patients with advanced or metastatic cancer. Thronicke A, Steele ML, Grah C, Matthes B, Schad F (2017). BMC Complementary and Alternative Medicine 17:534. 10 pp. DOI: 10.1186/s12906-017-2045-0
Immune-related and adverse drug reactions to low versus high initial doses of Viscum album L. in cancer patients. Schad F, Thronicke A, Merkle A, Matthes H, Steele ML (2017). Phytomedicine 36, 54-58. DOI: 10.2016/j.phymed.2017.09.004
Safety of intravenously applied mistletoe extract – results from a phase I dose escalation study in patients with advanced cancer. Huber R, Schlodder D, Effertz C, Rieger S, Tröger W (2017). BMC Complementary and Alternative Medicine 17:465. 8 pp. DOI: 10.1185/s12906-017-1971-1
Effects of mistletoe products on pharmacokinetic drug turnover by inhibition and induction of cytochrome P450 activities. Schink M, Dehus O (2017). BMC Complemetary and Alternative Medicine 17:521. 8 pp. DOI: 10.1186/s12096-017-2028-1
Impact of a combined multimodal-aerobic and multimodal intervention compared to standard aerobic treatment in breast cancer survivors with chronic cancerrelated fatigue - results of a three-armed pragmatic trial in a comprehensive cohort design. Kröz M, Reif M, Glinz A, Berger B, Nikolaou A, Zerm R, Brinkhaus B, Girke M, Büssing A, Gutenbrunner C, and On behalf of the CRF-2 study group. BMC Cancer (2017) 17:166. DOI 10.1186/s12885-017-3142-7. Full article Open Access: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335840/
Intravenous Mistletoe Treatment in Integrative Cancer Care: A Qualitative Study Exploring the Procedures, Concepts, and Observations of Expert Doctors. Kienle GS, Mussler M, Dieter Fuchs and Kiene H. Evidence-Based Complementary and Alternative Medicine, Volume 2016, Article ID 4628287, http://dx.doi.org/10.1155/2016/4628287
Health services research of integrative oncology in palliative care of patients with advanced pancreatic cancer. Axtner J , Steele M, Kröz M, Spahn G, Matthes H and Schad F. BMC Cancer (2016) 16:579 DOI 10.1186/s12885-016-2594-5. https://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2594-5
Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancer-related fatigue?
Kröz, M.; Reif, M.; Zerm, R.; Winter, K.; Schad. F.; Gutenbrunner, C.; Girke, M.; Bartsch, C. 2015. Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancerrelated fatigue? Eur J Cancer Care (Engl) 2015; 24(5): 707–717. doi:10.1111/ecc.12278. https://www.ncbi.nlm.nih.gov/pubmed/25602030
Mistletoe: From Basic Research to Clinical Outcomes in Cancer and Other Indications. Kröz M, Kienle GS, Feder G, Kaveri S and Rosenzweig S. Editorial. Evidence-Based Complementary and Alternative Medicine 2014, Article ID 987527. http://dx.doi.org/10.1155/2014/987527
Use and Safety of Intratumoral Application of European Mistletoe (Viscum album L) Preparations in Oncology. Steele ML, Axtner J, Happe A, Kröz, M, Matthes, H and Schad F. Integr Cancer Ther March 2015 vol. 14 no. 2 140-148. DOI: 10.1177/1534735414563977 ict.sagepub.com.
Safety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study. Steele ML, Axtner J, Happe A, Kröz, Matthes and Schad F. Evidence-Based Complementary and Alternative Medicine, 2014; Article ID 236310. Volume 2014,http://dx.doi.org/10.1155/2014/236310
Interaction of standardized mistletoe (Viscum album) extracts with chemotherapeutic drugs regarding cytostatic and cytotoxic effects in vitro. Weissenstein U , Kunz M , Urech K and Baumgartner S. BMC Complementary and Alternative Medicine 2014, 14 :6 Open access: http://www.biomedcentral.com/1472-6882/14/6
Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients. Steele ML, Axtner J, Happe A, Kröz M, Matthes H and Schad F. Evidence-Based Complementary and Alternative Medicine Volume 2014, Article ID 724258, 11 pages http://dx.doi.org/10.1155/2014/724258
Viscum album [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: A randomised clinical trial on overall survival. Tröger W, Galun M, Reif A et al. Eur J Cancer (2013) http://dx.doi.org/10.1016/j.ejca.2013.06.043
NCCAM/NCI Phase 1 Study of Mistletoe Extract and Gemcitabine in Patients with Advanced Solid Tumors. Mansky PJ, Wallerstedt DB, Sannes TS et al. Evidence-Based Complementary and Alternative Medicine Volume 2013, Article ID 964592, http://dx.doi.org/10.1155/2013/964592
Intratumoral Mistletoe (Viscum album L) Therapy in Patients With Unresectable Pancreas Carcinoma - A Retrospective Analysis. Schad F, Axtner J, Buchwald D, Happe A, Popp S, Kröz M and Matthes H. Integr Cancer Ther 2013 DOI: 10.1177/1534735413513637) http://ict.sagepub.com/content/early/2013/12/18/1534735413513637
Network Oncology (NO) – a Clinical Cancer Register for Health Services Research and the Evaluation of Integrative Therapeutic Interventions in Anthroposophic Medicine. Schad F, Axtner J, Happe A, Breitkreuz T, Paxino C, Gutsch J, Matthes B, Debus M, Kröz M, Spahn G, Riess H, von Laue H and Matthes H. Forsch Komplementmed 2013;20:353–360 Published online: October 24, 2013 DOI: 10.1159/000356204 Accessible online at: www.karger.com/fok
Anthroposophic supportive treatment in children with medulloblastoma receiving first-line therapy. Seifert G, Rutkowski S, Jesse P, Madeleyn R, Reif M, Henze G and Längler A. J Pediatr Hematol Oncol 2011;33(3):105-10 read more...
Anthroposophic Medicine in Paediatric Oncology in Germany: Results of a Population-Based Retrospective Parental Survey. Alfred Längler, Claudia Spix, Friedrich Edelhäuser, David D. Martin, Genn Kameda, Peter Kaatsch and Georg Seifert. Pediatr Blood Cancer 2010 DOI 10.1002/pbc. read more...
Retrospective analysis of patients with advanced pancreatic cancer under palliative treatment and additive intratumoral application of viscum album l. F. Schad, D. Buchwald, A. Merkle, S. Popp, M. Kroez, H. Matthes: J Clin Oncol 29: 2011 (suppl; abstract e14538). online:http://abstract.asco.org/AbstView_102_82630.
Evaluation of quality of life/life satisfaction in women with breast cancer in complementary and conventional care. Carlsson M, Arman M, Backman M, Flatters U, Hatschek T, Hamrin E. Acta Oncol. 2004;43(1):27-34.
Influence of Viscum album L (European Mistletoe) Extracts on Quality of Life in Cancer Patients: A Systematic Review of Controlled Clinical Studies.Kienle GS and Kiene H. Integrative Cancer Therapies 2010:1-16.
Molecular mistletoe therapy: friend or foe in established anti-tumor protocols? A multicenter, controlled, retrospective pharmaco-epidemiological study in pancreas cancer. Matthes H, Friedel WE, Bock PR, Zanker KS. Curr Mol Med 2010; 10: 430-9.read more...
Durable tumour responses following primary high dose induction with mistletoe extracts: Two case reports. Orange M, Fonseca M, Lace A, vonLaue HB, Geider S. European Journal of Integrative Medicine 2010;2:63-69.read more...
The influence of self- and autonomic regulation on cancer-related fatigue and distress in breast and colorectal cancer patients - A prospective study.Kröz M, Zerm R, Kuhnert N, Brauer D, Laue HBv, Bockelbrink A, Reif M, Schad F, Feder G, Heckmann C, Laue von S, Willich S, Girke M. European Journal of Integrative Medicine 2009;1(4):182. read more...
Prospective controlled cohort studies on long-therapy of cervical cancer patients with a mistletoe preparation (Iscador). Grossarth-Maticek R, Ziegler R.. Forsch Komplementärmed 2007;14:140-7.
A five-year follow-up of quality of life in women with breast cancer in anthroposophic and conventional care. Carlsson M, Arman M, Backman M, Flatters U, Hatschek T, Hamrin E. eCam 2006.
Coping in women with breast cancer in complementary and conventional care over 5 years measured by the mental adjustment to cancer scale.Carlsson M, Arman M, Backman M, Hamrin E. J Altern Complement Med 2005;11(3):441-447
Long-term outcomes of anthroposophic treatment for chronic disease: a four-year follow-up analysis of 1510 patients from a prospective observational study in routine outpatient settings. Hamre HJ, Kiene H, Glockmann A, Ziegler R, Kienle GS. BMC Res Notes 2013;6(269):doi:10.1186/1756-0500-6-269.
Anthroposophic therapies in chronic disease: the Anthroposophic Medicine Outcomes Study (AMOS) Hamre HJ, Becker-Witt C, Glockmann A, Ziegler R, Willich SN, Kiene H. Eur J Med Res. 2004 Jul 30;9(7):351-60. read more.
Anthroposophic therapy for children with chronic disease: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Meinecke C, Glockmann A, Willich SN, Kiene H. BMC Pediatr 2009;9:39 read more
Predictors of outcome after 6 and 12 months following anthroposophic therapy for adult outpatients with chronic disease: a secondary analysis from a prospective observational study. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Willich SN, Kiene H. BMC Research Notes 2010 Aug 3;3(218). read more
Long-term outcomes of anthroposophic therapy for chronic low back pain: A two-year follow-up analysis. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Ziegler R, Willich SN, Kiene H. Journal of Pain Research 2009;2:75-85. read more
Outcome of anthroposophic medication therapy in chronic disease: A 12-month prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Kienle GS, Willich SN, et al. Drug Design, Development and Therapy 2008;2:25-37.
Anthroposophic vs. conventional therapy for chronic low back pain: a prospective comparative study. Hamre H, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Eur J Med Res 2007;12:302-10.
Anthroposophic medical therapy in chronic disease: a four-year prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. BMC Complement Altern Med 2007;7(10):DOI 10.1186/1472-6882-7-10.
Integrative versus Conventional Therapy of Chronic Otitis Media with Effusion and Adenoid Hypertrophyin Children: A Prospective Observational Study. Szoeke H, Maródi M, Sallay Z, Székely B, Sterner MG and Hegyi G.: Forsch Komplementmed 2016;23:231–239. DOI: 10.1159/000448440. http://www.karger.com/Article/PDF/448440
Use and safety of anthroposophic medications for acute respiratory and ear infections: a prospective cohort study. Hamre HJ, Glockmann A, Fischer M, Riley D, Baars E, Kiene H. . Drug Target Insights 2007;2:209-19.
Integrative versus Conventional Therapy of Chronic Otitis Media with Effusion and Adenoid Hypertrophyin Children: A Prospective Observational Study. Szoeke H, Maródi M, Sallay Z, Székely B, Sterner MG and Hegyi G.: Forsch Komplementmed 2016;23:231–239. DOI: 10.1159/000448440. http://www.karger.com/Article/PDF/448440
Improvement of Asthma and Gastroesophageal Reflux Disease With Oral Pulvis stomachicus cum Belladonna, a Combination of Matricaria recutita, Atropa belladonna, Bismuth, and Antimonite: A Pediatric Case Report. von Schoen-Angerer T, Madeleyn R, Kiene H, Kienle GS, Vagedes J. 2015 http://www.gahmj.com/doi/full/10.7453/gahmj.2015.019
Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions. Hamre HJ, Glockmann A, Schwarz R, Riley DS, Baars EW, Kiene H and Kienle GS. Evidence-Based Complementary and Alternative Medicine Volume 2014 (2014), Article ID 243801, 17 pages Full article open access: http://dx.doi.org/10.1155/2014/243801
Anthroposophic therapy for children with chronic disease: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Meinecke C, Glockmann A, Willich SN, Kiene H. BMC Pediatr 2009;9:39 read more
Anthroposophic therapy for attention deficit hyperactivity: a two-year prospective study in outpatients. Harald J Hamre, Claudia M Witt, Gunver S Kienle, Christoph Meinecke, Anja Glockmann, Renatus Ziegler, Stefan N Willich, Helmut Kiene. International Journal of General Medicine 2010:3 239–253.
Course of life satisfaction in patients with depressive and addictive disorders after therapeutic intervention. Büssing A, Heusser P, Mundle G: International Journal of Social Psychiatry 2011; first published on March 25, 2011 as doi:10.1177/0020764010390498
Anthroposophic therapy for anxiety disorders: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Ziegler R, Willich SN, Kiene H. Clinical Medicine: Psychiatry 2009;2:17-31 read more...
Chemical pleurodesis using doxycycline and Viscum album extract.Song KS, Keum DY, Kim JB (2017) Korean Journal of Thoracic and Cardiovascular Surgery 50 (4), 281-286. DOI: 10.5090/kjtcs.2017.50.4.281
The management of chemical pleurodesis with Viscum album in patients with persistent air leakage. Park JB, Lee SA, Lee WS, Kim YH, Hwang JJ (2018) The management of chemical pleurodesis with Viscum album in patients with persistent air leakage. Journal of Thoracic Disease 10 (1), 371-376. Read more
Improvement of Asthma and Gastroesophageal Reflux Disease With Oral Pulvis stomachicus cum Belladonna, a Combination of Matricaria recutita, Atropa belladonna, Bismuth, and Antimonite: A Pediatric Case Report. von Schoen-Angerer T, Madeleyn R, Kiene H, Kienle GS, Vagedes J. 2015 http://www.gahmj.com/doi/full/10.7453/gahmj.2015.019
Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions. Hamre HJ, Glockmann A, Schwarz R, Riley DS, Baars EW, Kiene H and Kienle GS. Evidence-Based Complementary and Alternative Medicine Volume 2014 (2014), Article ID 243801, 17 pages Full article open access: http://dx.doi.org/10.1155/2014/243801
Anthroposophic therapy for asthma: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Schnürer C, Glockmann A, Ziegler R, Willich SN, Kiene H.J Asthma Allergy 2009;2:111-28.
Use and safety of anthroposophic medications for acute respiratory and ear infections: a prospective cohort study. Hamre HJ, Glockmann A, Fischer M, Riley D, Baars E, Kiene H. . Drug Target Insights 2007;2:209-19.
Anthroposophic Medicine is integrative medicine
CAM treatments for cough and sore throat as part of an uncomplicated acute respiratory tract infection: a systematic review of prescription rates and a survey among European integrative medical practitioners. Baars EW, Belt-Van Zoen E, Willcox M,Huber R, Xiao-Yang Hu and van der Werf ET. European Journal of Integrative Medicine 2020;39: 101194, ISSN 18763820.
https://doi.org/10.1016/j.eujim.2020.101194
Inverse relationship between reduced fatigue and severity of anemia in oncology patients treated with integrative medicine: understanding the paradox. Ben-Arye E, Dahan O, Shalom-Sharabi I, Samuels N (2018) Supportive Care in Cancer. 10 pp. DOI: 10.1007/s00520-018-4271-5
Complementary and alternative medicine for cancer patients: results of the EPAAC survey on integrative oncology centres in Europe. Rossi, E.; Vita, A.; Baccetti, S.; Di Stefano, M.; Voller, F.; Zanobini, A. 2015. Complementary and alternative medicine for cancer patients: results of the EPAAC survey on integrative oncology centres in Europe. Support Care Cancer 23(6): 1795–1806. doi:10.1007/s00520-014-2517-4. https://www.ncbi.nlm.nih.gov/pubmed/25471177
Influence of spirituality on cool down reactions, work engagement, and life satisfaction in anthroposophic health care professionals. Büssing A, Lötzke D, Glöckler M, Heusser P. 2015. Influence of spirituality on cool down reactions, work engagement, and life satisfaction in anthroposophic health care professionals. Evid Based Complement Alternat Med. doi: 10.1155/2015/754814. https://www.hindawi.com/journals/ecam/2015/754814/
Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancer-related fatigue?
Kröz, M.; Reif, M.; Zerm, R.; Winter, K.; Schad. F.; Gutenbrunner, C.; Girke, M.; Bartsch, C. 2015. Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancerrelated fatigue? Eur J Cancer Care (Engl) 2015; 24(5): 707–717. doi:10.1111/ecc.12278. https://www.ncbi.nlm.nih.gov/pubmed/25602030
Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions. Hamre HJ, Glockmann A, Schwarz R, Riley DS, Baars EW, Kiene H and Kienle GS. Evidence-Based Complementary and Alternative Medicine Volume 2014 (2014), Article ID 243801, 17 pages Full article open access: http://dx.doi.org/10.1155/2014/243801
Patients whose GP knows complementary medicine tend to have lower costs and live longer. Peter Kooreman P and Baars EW (2010): Eur J Health Econ DOI 10.1007/s10198-011-0330-2
Anthroposophic Medicine: An Integrative Medical System Originating in Europe. Kienle GS, Albonico H-U, Baars, Hamre HJ, Zimmermann P and Kiene H. Global Adv Health Med. 2013;2(6):20-31. DOI: 10.7453/gahmj.2012.087
Overview of the Publications From the Anthroposophic Medicine Outcomes Study (AMOS): A Whole System Evaluation Study. Hamre HJ, Kiene H, Ziegler R, Tröger W, Meinecke C, Schnürer C, Vögler H, Glockmann A, Kienle S: Global Adv Health Med. 2014;3(1):54-70. DOI: 10.7453/gahmj.2013.010.
Full article: http://www.gahmj.com/doi/pdf/10.7453/gahmj.2013.010
Opposite Drug Prescription and Cost Trajectories following Integrative and Conventional Care for Pain – A Case-Control Study. Sundberg, Petzold M, Kohls N and Falkenberg T. PLoS ONE 2014; 9(5): e96717. doi:10.1371/journal.pone.0096717.
Complementary Therapy Systems and Their Integrative Evaluation. Kienle GS, Albonico H-U, Fischer L, Frei-Erb M, Hamre HJ, Heusser P, Matthiessen PF, Renfer A, Kiene H. Journal of Science and Healing 2011(7/3): 175-187. read more (free download)
Clinical judgement and the medical profession. Gunver S Kienle and Helmut Kiene. Journal of Evaluation in Clinical Practice 2010: doi:10.1111/j.1365-2753.2010.01560.x read more
Mindfulness-Based Stress Reduction (MBSR) for integrative Cancer Care – A summary of evidence. Musial F, Büssing A, Heusser P, Kyung-Eun C, Ostermann T: Forschende Komplementärmedizin 2011; 18: (Online August 8, 2011; DOI: 10.1159/000330714)
The challenges of complexity. Wolf U, Winkler M, Ephraim M, Hamre HJ, Lemann D: Primary Care 2011; 11(10):174-175.
Professional treatment in the context of medical pluralism - A German perspective. Kiene H, Brinkhaus B, Fischer G, Girke M, Hahn EG, Hoppe HD, Jütte R, Kraft K, Klitzsch W, Matthiessen PF, Meister P, Michalsen A, Teut M, Willich SN, Heimpel H. Europaen Journal of Integrative Medicine 2010;2:53-56 read more
A pilot study on the effects of a team building process on the perception of work environment in an integrative hospital for neurological rehabilitation. Ostermann T, Bertram M, Büssing A BMC Complementary and Alternative Medicine 2010; 10, 10 (http://www.biomedcentral.com/1472-6882/10/10: 25-44) (pp. 1-10) read more
An integrative approach of cancer treatment with mistletoe therapy, surgery, irradiation and chemotherapy in CAM settings. Schad F, Merkle A, Hoffmann G, Lenneweit G, Spahn G, Hesse M, Paxino C, Wellmann G, Matthes B, Baute R, Breitkreuz T, Matthes H. European Journal of Integrative Medicine 2009;1(4):184. read more
Integrative medical education: Educational strategies and preliminary evaluation of the Integrated Curriculum for Anthroposophic Medicine (ICURAM). Scheffer C, et al. Patient Educ Couns (2012), read more
Medicinal Systems of Complementary and Alternative Medicine: A Cross-Sectional Survey at a Pediatric Emergency Department. Zuzak J, Zuzak-Siegrist I, Rist L, Staubli G, Simoñes-Wüst AP. The Journal of Alternative and Complementary Medicine, Volume 16, Number 4, 2010, pp. 473-479.
Anthroposophic perspectives in primary care. Cantor IS, Rosenzweig S, Volume 24, Number 4, December 1997.
Eurythmy therapy
Development of a Documentation Instrument for Movement-orientated Mind-Body-Therapies Taking the Example of Eurythmy-Therapy. Gerlach K, Rodrigues Recchia D, Büssing A. Complementary Therapies in Medicine 2019;44:91-93. DOI: https://doi.org/10.1016/j.ctim.2019.04.004
Training effect of eurythmy therapy on specific oscillations of heart rate variability.
Edelhäuser, F.; Minnerop, A.; Trapp, B.; Büssing, A.; Cysarz, D. 2015. Eurythmy therapy increases specific oscillations of heart rate variability. BMC Complement Altern Med 2015: 167. doi:10.1186/s12906-015-0684-6. http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0684-6
A systematic literature review on the effectiveness of eurythmy therpy.
Lötzke D, Heusser P, Büssing A. J Integr Med. 2015 Jul;13(4):217-30. doi: 10.1016/S2095-4964(15)60163-7. http://www.ncbi.nlm.nih.gov/pubmed/25808905
Eurythmy therapy increases specific oscillations of heart rate variability. Edelhäuser F, Antje Minnerop A, Trapp B, Büssing A 3 and Cysarz D. BMC Complementary and Alternative Medicine (2015) 15:167 DOI 10.1186/s12906-015-0684-6. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457978/
Eurythmy Therapy in Anxiety. Schwab J, Murphy J, Andersson P, Lunde G, Kiene H, Hamre HJ, Kienle GS: Alternative Therapies in Health and Medicine 2011;17(4): 58-65. Read more
Inner Correspondence and Peacefulness with Practices among Participants in Eurythmy Therapy and Yoga: A Validation Study. Büsssing A, Edelhäuser F, Weisskircher A, Fouladbakhsh JM and Heusser P. Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Volume 2011, Article ID 329023, 9 pages doi:10.1155/2011/329023 read more
Therapeutic Eurythmy-movement therapy for children with attention deficit hyperactivity disorder (ADHD): a pilot study. Majorek M, Tuchelmann T, Heusser P. Complement Ther Nurs Midwifery 2004 10(1):46-53.
Effects of complementary eurythmy therapy on heart rate variability. Seifert et al:, Complement Ther Med (2008), doi:10.1016/j.ctim.2008.09.005)
Eurythmy therapy in chronic disease: a four-year propective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. BMC Public Health 2007;7(61):DOI 10.1186/1471-2458-7-61.
External applications, nursing, massage
Clinical Outcomes of Rhythmical Massage. A Prospective Cohort Study with Swiss Outpatients. Wälchli C, Saltzwedel G, Rist L, Bach-Meguid B, Eberhard J, Decker M and Simões-Wüst AP. Alternative and Complementary Therapies. October 2014, 20(5): 248-258. doi:10.1089/act.2014.20509. http://online.liebertpub.com/doi/abs/10.1089/act.2014.20509
Rhythmical massage therapy in chronic disease: a four-year prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. J Altern Complement Med 2007;13(6):635-42.
Therkleson T, Sherwood P: Patient’s experience of the external therapeutic application of ginger by anthroposophically trained nurses. Indio-Pacific Journal of Phenomenology 2005;4:1-11.
Anthroposophic art therapies
The Anthroposophic Art Therapy Assessment Paint (AART-ASSESS-P): A peer-report instrument to assess patients' pictorial expression during Anthroposophic Painting Therapy.Mehl A, Brauer D, Didwiszus A, Gelin-Kröz B, Pranga D, Zerm R, Gutenbrunner C, Reif M and Kröz M: Explore (NY) 2020. doi: 10.1016/j.explore.2020.07.007
Reliability and First Validity of the Inner Correspondence Questionnaire for Painting Therapy (ICPTh) in a Sample of Breast Cancer Patients. Kröz M, Mehl A, Didwiszus A, Gelin-Kröz B, Reif M, Berger B, Ten Brink F, Zerm R, Girke M, Gutenbrunner C, Büssing A. Complementary Therapies in Medicine 2019;42(2):355-360. DOI: https://doi.org/10.1016/j.ctim.2018.12.002
Effects of live music therapy on heart rate variability and selfreported stress and anxiety among hospitalized pregnant women: A randomized controlled trial. Teckenberg-Jansson P, Turunen S, Pölkki T, Lauri-Haikala M-J, Lipsanen J, Henelius A, Aitokallio-Tallberg A, Pakarinen S, Leinikka M and Huotilainen M. Nordic Journal of Music Therapy 2019, 28:1, 7-26. DOI: 10.1080/08098131.2018.1546223
Speech-guided breathing retraining in asthma: a randomised controlled crossover trial in real-life outpatient settings. Von Bonin D, Klein SD, Würker, Streit E, Avianus O, Grah C, Salomon J and Wolf Ucorresponding author. BioMedCentral. Published online 2018 Jun 25. doi: 10.1186/s13063-018-2727-z. Open access
Arts Therapies for Anxiety, Depression, and Quality of Life in Breast Cancer Patients: A Systematic Review and Meta-Analysis. Boehm K, Cramer H, Staroszynski T and Ostermann T: Hindawi Publishing Corporation. Evidence-Based Complementary and Alternative Medicine.Volume 2014, Article ID 103297, 9 pages http://dx.doi.org/10.1155/2014/103297
Anthroposophic art therapy in chronic disease: a four-year prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Explore 2007;3(4):365-71.
Oscillations lf heart rate and respiration synchronize during poetry recitation. Cysarz D, von Bonin D, Lackner H, Heusser P, Moser M, Bettermann H: Am J Physiol Heart Circ Physiol 2004;287:H579-H58
Anthroposophic lifestyle
Allergic disease and sensitization in Steiner school children. Floistrup H, Swartz J, Bergstrom A, Alm JS, Scheynius A, van Hage M, Waser M, Braun-Fahrlander C, Schram-Bijkerk D, Huber M, et al. J Allergy Clin Immunol 2006;117(1):59-66.
Bacterial and fungal agents in house dust and wheeze in children: the PARSIFAL study. Schram-Bijkerk D, Doekes G, Douwes J, Boeve M, Riedler J, Ublagger E, von Mutius E, Benz MR, Pershagen G, van Hage M, et al. Clin Exp Allergy 2005;35(10):1272-1278.
Bacterial and fungal components in house dust of farm children, Rudolf Steiner school children and reference children--the PARSIFAL Study.Schram D, Doekes G, Boeve M, Douwes J, Riedler J, Ublagger E, von Mutius E, Budde J, Pershagen G, Nyberg F, et al. Allergy 2005;60(5):611-618.
An anthroposophic lifestyle and intestinal microflora in infancy. Alm JS, Swartz J, Bjorksten B, Engstrand L, Engstrom J, Kuhn I, Lilja G, Mollby R, Norin, E, Pershagen G, Reinders C, Wreiber K, Scheynius A . Pediatr Allergy Immunol 2002;13(6) :402-11.
Atopy in children of families with an anthroposophic lifestyle. Alm JS, Swartz j, Lilja G, Scheynius A, Pershagen G . Lancet 1999;353(9163) :1485-8.
Basic and preclinical research
Aviscumine, a recombinant ribosomal inhibitor, increases the antitumor activity of natural killer cells.Gamerith G, Amann A, Schenk B, Auer T, Lentzen H, Mügge DO, Cima KM, Löffler-Ragg J, Hilbe W, Zwierzina H (2017) Oncology Letters 14 (5), 5563-5568. DOI: 10.3892/ol.2017.686
Synergistic antitumour properties of viscumTT in alveolar rhabdomyosarcoma. Stammer RM, Kleinsimon S, Rolff J, Jäger S, Eggert A, Seifert G, Delebinski CI (2017) Journal of Immunology Research 2017. 13 pp. Article ID 4874280. DOI: 10.1155/2017/4874280
Immunomodulatory effects of preparations from anthroposophical medicine for parenteral use. Gründemann, C.; Diegel, C.; Sauer, B.; Garcia-Käufer, M.; Huber, R. 2015. Immunomodulatory effects of preparations from Anthroposophical Medicine for parenteral use. BMC Complement Altern Med 15: 219. doi:10.1186/s12906-015-0757-6. http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0757-6
Cytotoxic properties of Helleborus niger L. on tumour and immunocompetent cells. Schink, M.; Garcia-Käufer, M.; Bertrams, J.; Duckstein, S.M.; Müller, M.B.; Huber, R.; Stintzing, F.C.; Gründemann, C. 2015. Differential cytotoxic properties of Helleborus niger L. on tumour and immunocompetent cells. J Ethnopharmacol 159: 129–136. doi:10.1016/j.jep.2014.11.003. http://europepmc.org/abstract/med/25446603
Effects of chronic Bryophyllum pinnatum administration on Wistar rat pregnancy. Hosomi, J.K.; Ghelman, R.; Quintino, M.P.; de Souza, E.; Nakamura, M.; Moron, A.F. 2014. Effects of chronic Bryophyllum pinnatum administration on Wistar rat pregnancy. Forsch Komplementärmed 21(3): 184–189. doi:10.1159/000363709. https://www.karger.com/Article/Pdf/363709
Preclinical assays to investigate an anthroposophic pharmaceutical process applied to mistletoe. Baumgartner, S.; Flückiger, H.; Kunz, M.; Scherr, C.; Urech, K. 2014. Evaluation of Preclinical Assays to Investigate an Anthroposophic Pharmaceutical Process Applied to Mistletoe (Viscum album L.) Extracts. Evid Based Complement Alternat Med 2014: 620974. doi:10.1155/2014/620974. https://www.hindawi.com/journals/ecam/2014/620974/
Two new flavonol glycosides and a metabolite profile of Bryophyllum pinnatum.Fürer, K.; Raith, M.; Brenneisen, R.; Mennet, M.; Simoes-Wüst, A.P.; von Mandach, U.; Hamburger, M.; Potterat, O. 2013. Two new flavonol glycosides and a metabolite profile of Bryophyllum pinnatum, a phytotherapeutic used in obstetrics and gynaecology. Planta Med. 79(16): 1565–1571. doi:10.1055/s-0033-1350808. https://www.ncbi.nlm.nih.gov/pubmed/24072500
Comparative in vitro study of the effects of separate and combined products of Citrus e fructibus and Cydonia e fructibus on immunological parameters of seasonal allergic rhinitis. Baars, E.W.; Jong, M.C.; Boers, I.; Nierop, A.F.; Savelkoul, H.F. 2012. A comparative in vitro study of the effects of separate and combined products of Citrus e fructibus and Cydonia e fructibus on immunological parameters of seasonal allergic rhinitis. Mediators Inflamm. 2012: 109829. doi:10.1155/2012/109829. https://www.hindawi.com/journals/mi/2012/109829/
Homeopathic preparations of quartz, sulfur and copper sulfate assessed by UV-spectroscopy. Wolf, U.; Wolf, M.; Heusser, P.; Thurneysen, A.; Baumgartner, S. 2011. Homeopathic Preparations of Quartz, Sulfur and Copper Sulfate Assessed by UV-Spectroscopy. Evid Based Complement Alternat Med 2011: 692798. doi:10.1093/ecam/nep036. https://www.hindawi.com/journals/ecam/2011/692798/
Immunomodulatory properties of a lemon-quince preparation as an indicator of anti-allergic potency. Gründemann, C.; Papagiannopoulos, M.; Lamy, E.; Mersch-Sundermann, V.; Huber, R. 2011. Immunomodulatory properties of a lemon-quince preparation (Gencydo®) as an indicator of anti-allergic potency. Phytomedicine 18(8–9): 760–768. doi:10.1016/j.phymed.2010.11.016. https://www.ncbi.nlm.nih.gov/pubmed/21256726
For further study results on basic and preclinical research browse: Verein für Krebsforschun e.V. Arlesheim (CH) http://www.vfk.ch/l/aktlit80
Further information/Databases/Links
Forschungsinstitut Havelhöhe, Berlin www.fih-berlin.de/html/publikationen.html
Lehrstuhl für Medizintheorie, Integrative und Anthroposophische Medizin, Witten/Herdecke www.uni-wh.de/gesundheit/lehrstuhl-medizintheorie/forschung/
Institute for Applied Epistemology and Medical Methodology at the University of Witten/Herdecke, Freiburg www.ifaemm.de/F5_publi.htm
The Anthroposophic Medicine site Anthromedics
Verein für Krebsforschun e.V. Arlesheim (CH): http://www.vfk.ch/l/aktlit80
Suomen Antroposofisen Lääketieteen Lääkäriyhdistys ry SALLY, www.antroposofinenlaaketiede.fi
International Federation of Anthroposophic Medical Associations IVAA, www.ivaa.info
Vapa hengentieteellinen korkeakoulu, Lääketieteellinen osasto, Goetheanum, Dornach, Sveitsi www.medsektion-goetheanum.org