Integratiivinen lääketiede ja terveydenhuolto / Täydentävät terveysnäkemykset EU:ssa

www.cam-europe.eu

CAM-Interest
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Seminaarit EU-Parlamenttissa

Lisätiedot: ohjelmat, esitelmät, julkaisut ,ym..

CAM konferenssit
EU-Parlamenttissa

Konferenssi 9.10.2012

Lisätiedot: ohjelma, esitelmät, julkaisut, ym...

EUROCAM on Facebook
Uutiset ja keskustelu

Tuorein CAM-Interest-Group kokous 1.7.2015
"Ensuring the availability of CAM medicinal products"
pj: Sirpa Pietikäinen


Tutkimuswww.cambrella.eu

Päätöskonferensin esitelmät, yhteenveto, julkaisut


CAM-LÄÄKÄRIT

www.camdoc.eu

Julkaisut



 


English


Integratiivinen lääketiede ja terveydenhuolto / Täydentävät terveysnäkemykset Suomessa

Tutkimusseminaari:

Täydentävät ja vaihtoehtoiset hoidot CAM Tieteellinen tutkimus ja sen haasteet Suomessa

Tutkimusseminaari
Tampereen Yliopisto
Terveystieteiden yksikkö
13.11. 2015

Ohjelma
Luennot
Abstraktit
Materiaalit
Raportit, haastattelut ym.
lue lisää...

Keskustelu

Facebook: Täydentävät terveysnäkemykset

Bloggi: Täydentävät terveysnäkemykset


Kotimaiset ja kansainväliset konferenssit

International Congress for Integrative Health & Medicine, Suttgart, Germany. 9.-11. June 2016
Further information http://www.icihm.org/en

9th European Congress for Integrative Medicine (ECIM). The Future of Comprehensive Patient Care.
Budapest, Hungary, September 10-11th 2016 http://www.ecim-congress.org/


Vertaisarviointi-lehdet Integratiivisen lääketieteen alalla

Peer-review Journals publishing research on Integrative medicine

Kattava listaus lehdistä integratiivisen lääketieten alalta löytyy tästä: Complementary Therapies Journals Links


Usein siteeratut lehdet (lista ei ole täydellinen):

Forschende Komplementärmedizin / Research in Complementary Medicine

Advances in Integrative Medicine

BMC Complementary and Alternative Medicine

Complementary Therapies in Medicine

Complementary Therapies in Clinical Practice

European Journal of Integrative Medicine

Evidence-Based Complementary and Alternative Medicine eCAM

Global Advances in Health and Medicine

Integrative Medicine Insights

Journal of Alternative and Complementary Medicine


 

Ajassa / Actual Topics Anthroposophic Medicine

Impact of a combined multimodal-aerobic and multimodal intervention compared to standard aerobic treatment in breast cancer survivors with chronic cancerrelated fatigue - results of a three-armed pragmatic trial in a comprehensive cohort design. Kröz M, Reif M, Glinz A, Berger B, Nikolaou A, Zerm R, Brinkhaus B, Girke M, Büssing A, Gutenbrunner C, and On behalf of the CRF-2 study group. BMC Cancer (2017) 17:166. DOI 10.1186/s12885-017-3142-7. Full article Open Access: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335840/

Integrative versus Conventional Therapy of Chronic Otitis Media with Effusion and Adenoid Hypertrophyin Children: A Prospective Observational Study.
Szoeke H, Maródi M, Sallay Z, Székely B, Sterner MG and  Hegyi G.: Forsch Komplementmed 2016;23:231–239. DOI: 10.1159/000448440. http://www.karger.com/Article/PDF/448440

Intravenous Mistletoe Treatment in Integrative Cancer Care: A Qualitative Study Exploring the Procedures, Concepts, and Observations of Expert Doctors.
Kienle GS, Mussler M, Dieter Fuchs and Kiene H. Evidence-Based Complementary and Alternative Medicine, Volume 2016, Article ID 4628287, http://dx.doi.org/10.1155/2016/4628287

Patient-centered outcomes on quality of life and Anthroposophic healthcare: a qualitative triangulation study.
Koster EB, Baars EW and Delnoij DMJ. Qual Life Res. 2016. DOI 10.1007/s11136-016-1276-8 http://link.springer.com/article/10.1007/s11136-016-1276-8

Health services research of integrative oncology in palliative care of patients with advanced pancreatic cancer.
Axtner J , Steele M, Kröz M, Spahn G, Matthes H and Schad F. BMC Cancer (2016) 16:579 DOI 10.1186/s12885-016-2594-5. https://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2594-5

Effect of Colchicum autumnale in patients with goitre and euthyroidism or mild hyperthyroidism.
Scheffer, C.; Debus, M.; Heckmann, C.; Cysarz, D.; Girke, M. 2016. Colchicum autumnale in Patients with Goitre with Euthyroidism or Mild Hyperthyroidism: Indications for a Therapeutic Regulative Effect – Results of an Observational Study. Evid Based Complement Alternat Med 2016: 2541912. doi:10.1155/2016/2541912. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756131/

Anthroposophy and Integrative Care at the End of Life.
Ciro Augusto Floriani CA. Alternative and complementary therapies. 2016; 22(3): DOI: 10.1089/act.2016.29055.caf http://online.liebertpub.com/doi/abs/10.1089/act.2016.29055.caf

Complementary and alternative medicine for cancer patients: results of the EPAAC survey on integrative oncology centres in Europe.
Rossi, E.; Vita, A.; Baccetti, S.; Di Stefano, M.; Voller, F.; Zanobini, A. 2015. Complementary and alternative medicine for cancer patients: results of the EPAAC survey on integrative oncology centres in Europe. Support Care Cancer 23(6): 1795–1806. doi:10.1007/s00520-014-2517-4. https://www.ncbi.nlm.nih.gov/pubmed/25471177

Improvement of sleep quality during treatment with Bryophyllum.
Simoes-Wüst, A.P.; Hassani, T.A.; Müller-Hübenthal, B.; Pittl, S.; Kuck, A.; Meden, H.; Eberhard, J.; Decker, M.; Fürer, K.; von Mandach, U.; Bryophyllum Collaborative Group. 2015. Sleep Quality Improves During Treatment with Bryophyllum pinnatum: An Observational Study on Cancer Patients. Integr Cancer Ther 2015; 14(5): 452–459. doi:10.1177/1534735415580680. https://www.ncbi.nlm.nih.gov/pubmed/25873294

Immunomodulatory effects of preparations from anthroposophical medicine for parenteral use.
Gründemann, C.; Diegel, C.; Sauer, B.; Garcia-Käufer, M.; Huber, R. 2015. Immunomodulatory effects of preparations from Anthroposophical Medicine for parenteral use. BMC Complement Altern Med 15: 219. doi:10.1186/s12906-015-0757-6. http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0757-6 

Influence of spirituality on cool down reactions, work engagement, and life satisfaction in anthroposophic health care professionals.
Büssing A, Lötzke D, Glöckler M, Heusser P. 2015. Influence of spirituality on cool down reactions, work engagement, and life satisfaction in anthroposophic health care professionals. Evid Based Complement Alternat Med. doi: 10.1155/2015/754814. https://www.hindawi.com/journals/ecam/2015/754814/

Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancer-related fatigue?
Kröz, M.; Reif, M.; Zerm, R.; Winter, K.; Schad. F.; Gutenbrunner, C.; Girke, M.; Bartsch, C. 2015. Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancerrelated fatigue? Eur J Cancer Care (Engl) 2015; 24(5): 707–717. doi:10.1111/ecc.12278. https://www.ncbi.nlm.nih.gov/pubmed/25602030

Training effect of eurythmy therapy on specific oscillations of heart rate variability.
Edelhäuser, F.; Minnerop, A.; Trapp, B.; Büssing, A.; Cysarz, D. 2015. Eurythmy therapy increases specific oscillations of heart rate variability. BMC Complement Altern Med 2015: 167. doi:10.1186/s12906-015-0684-6. http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0684-6

Improvement of Asthma and Gastroesophageal Reflux Disease With Oral Pulvis stomachicus cum Belladonna, a Combination of Matricaria recutita, Atropa belladonna, Bismuth, and Antimonite: A Pediatric Case Report. von Schoen-Angerer T,  Madeleyn R, Kiene H, Kienle GS, Vagedes J. 2015 http://www.gahmj.com/doi/full/10.7453/gahmj.2015.019

A systematic literature review on the effectiveness of eurythmy therpy.
Lötzke D, Heusser P, Büssing A. J Integr Med. 2015 Jul;13(4):217-30. doi: 10.1016/S2095-4964(15)60163-7. http://www.ncbi.nlm.nih.gov/pubmed/25808905
“…Eurythmy therapy is a movement therapy of anthroposophic medicine that can have effects on a person's physical body, spirit, and soul. The aim of this publication was to update and summarize the relevant literature on the effectiveness of eurythmy in a therapeutic context since 2008. Conclusion: Eurythmy seems to be a beneficial add-on in a therapeutic context that can improve the health conditions of affected persons. More methodologically sound studies are needed to substantiate this positive impression.Read more…

Use and Safety of Intratumoral Application of European Mistletoe (Viscum album L) Preparations in Oncology.
Steele ML, Axtner J, Happe A, Kröz, M, Matthes, H and Schad F. Integr Cancer Ther March 2015 vol. 14 no. 2 140-148. DOI: 10.1177/1534735414563977 ict.sagepub.com.
"Intratumoral (IT) injection of European mistletoe (Viscum album L) preparations might induce local tumor response through combined cytotoxic and immunomodulatory actions of the preparations. The present study summarizes the practice and safety of off-label IT mistletoe therapy within the Network Oncology, a conjoint clinical registry of German hospitals and outpatients specialized in anthroposophic and integrative medicine. IT injection of mistletoe preparations resulted in a relatively high frequency of adverse drug reactions (ADRs). Nearly all ADRs were mild to moderate however, and no serious ADRs occurred. Furthermore, it is possible that immune-related ADRs such as pyrexia and local inflammatory reactions might be critical for tumor response. In light of these results, IT mistletoe therapy seems to be safe and prospective trials are recommended…”Read more…

Safety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study. Steele ML, Axtner J, Happe A, Kröz, Matthes and Schad F. Evidence-Based Complementary and Alternative Medicine, 2014; Article ID 236310. Volume 2014,http://dx.doi.org/10.1155/2014/236310
“...The frequency of adverse drug reactions (ADRs) to intravenous mistletoe applications was calculated and compared to ADR data from a study on subcutaneous applications. Results. Of 475 cancer patients who received intravenous infusions of Helixor, Abnoba viscum, or Iscador mistletoe preparations, 22 patients (4.6%) reported 32 ADRs of mild (59.4%) or moderate severity (40.6%). No serious ADRs occurred… Conclusion. Intravenous mistletoe therapy was found to be safe and prospective studies for efficacy are recommended…” read more…

Mistletoe: From Basic Research to Clinical Outcomes in Cancer and Other Indications. Kröz M, Kienle GS, Feder G, Kaveri S and Rosenzweig S. Editorial. Evidence-Based Complementary and Alternative Medicine 2014, Article ID 987527. http://dx.doi.org/10.1155/2014/987527 read more...

Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions. Hamre HJ, Glockmann A, Schwarz R, Riley DS, Baars EW, Kiene H and Kienle GS. Evidence-Based Complementary and Alternative Medicine Volume 2014 (2014), Article ID 243801, 17 pages Full article open access: http://dx.doi.org/10.1155/2014/243801
“…Children with acute respiratory or ear infections (RTI/OM) are often unnecessarily prescribed antibiotics. Antibiotic resistance is a major public health problem and antibiotic prescription for RTI/OM should be reduced. Anthroposophic treatment of RTI/OM includes anthroposophic medications, nonmedication therapy and if necessary also antibiotics. This secondary analysis from an observational study comprised 529 children <18 years from Europe (AT, DE, NL, and UK) or USA, whose caregivers had chosen to consult physicians offering anthroposophic (A-) or conventional (C-) treatment for RTI/OM. Compared to C-patients, A-patients also had much lower use of analgesics, somewhat quicker symptom resolution, and higher caregiver satisfaction. Adverse drug reactions were infrequent (2.3% in both groups) and not serious.” Read more…

Antimicrobial resistance (AMR) and anthroposophic health care
The increasing importance of the antimicrobial resistance problem is a global issue that could offer a potential field for anthroposophic health care to show its role and to collaborate with other fields.
> Read more...

Integrative Medicine - Applying corporate culture principles from mergers
This interesting topic is been researched by Claudia Witt and will be one of the topics to be further discussed at the International Scientific Congress on anthroposophic medicine in 2014.
> Read more...

Patients whose GP knows complementary medicine tend to have lower costs and live longer. Peter Kooreman P and Baars EW (2010): Eur J Health Econ DOI 10.1007/s10198-011-0330-2
“…Results Patients whose GP has additional CAM training have 0–30% lower healthcare costs and mortality rates, depending on age groups and type of CAM. The lower costs result from fewer hospital stays and fewer prescription drugs…”


Katsaukset

Anthroposophic Medicine: An Integrative Medical System Originating in Europe. Kienle GS, Albonico H-U, Baars, Hamre HJ, Zimmermann P and Kiene H. Global Adv Health Med. 2013;2(6):20-31. DOI: 10.7453/gahmj.2012.087
…Anthroposophic medicine is an integrative multimodal treatment system based on a holistic understanding of man and nature and of disease and treatment…. Anthroposophic healthcare is provided by medical doctors, therapists, and nurses. A Health-Technology Assessment Report and its recent update identified 265 clinical studies on the efficacy and effectiveness of anthroposophic medicine. The outcomes were described as predominantly positive. These studies as well as a variety of specific safety studies found no major risk but good tolerability. Economic analyses found a favorable cost structure. Patients report high satisfaction with anthroposophic healthcare.”

Overview of the Publications From the Anthroposophic Medicine Outcomes Study (AMOS): A Whole System Evaluation Study. Hamre HJ, Kiene H, Ziegler R, Tröger W, Meinecke C, Schnürer C, Vögler H, Glockmann A, Kienle S: Global Adv Health Med. 2014;3(1):54-70. DOI: 10.7453/gahmj.2013.010.
Full article: http://www.gahmj.com/doi/pdf/10.7453/gahmj.2013.010
”… A total of 21 peer-reviewed publications from AMOS have resulted. This article provides an overview of the main research questions, methods, and findings from these publications: anthroposophic treatment was safe and was associated with clinically relevant improvements in symptoms and quality of life without cost increase; improvements were found in all age, diagnosis, and therapy modality groups and were retained at 48-month follow-up; nonrespondent bias, natural recovery, regression to the mean, and adjunctive therapies together could explain a maximum of 37% of the improvement…“


Alkuperäistutkimukset

Eurythmy therapy increases specific oscillations of heart rate variability. Edelhäuser F, Antje Minnerop A, Trapp B, Büssing A 3 and Cysarz D. BMC Complementary and Alternative Medicine (2015) 15:167 DOI 10.1186/s12906-015-0684-6. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457978/
“…In this study, the simultaneous effects of two different Eurythmy therapy (EYT) exercises on cardiac autonomic regulation as assessed by spectral analysis of heart rate variability (HRV) were investigated. Conclusions: The repetition of the sequence of body movements of both EYT exercises clearly affected cardiac autonomic regulation in a rhythmic manner according to the stimulus of the specific body movements of each EYT exercise. These results offer a physiological basis to develop a rationale for specific clinical indications of these EYT exercises such as stress reduction or prevention of hypertension.” Read more…

Clinical Outcomes of Rhythmical Massage. A Prospective Cohort Study with Swiss Outpatients. Wälchli C, Saltzwedel G, Rist L, Bach-Meguid B, Eberhard J, Decker M and Simões-Wüst AP. Alternative and Complementary Therapies. October 2014, 20(5): 248-258. doi:10.1089/act.2014.20509. http://online.liebertpub.com/doi/abs/10.1089/act.2014.20509 “…Rhythmical massage (RM) is a form of massage therapy extensively used in anthroposophic medicine (AM). Here, RM’s use and impact on clinical outcomes was investigated in a prospective observational study performed with patients from a Swiss hospital and an associated group practice. Clinical outcomes were assessed with Disease and Symptom Scores, the Health-Related Quality-of-Life (HRQoL) questionnaire Short Form–36 (SF-36), and Goal Attainment Scaling (GAS). Patients receiving RM for any indication in an anthroposophic medicine setting perceived reductions of symptoms accompanied by improvements of HRQoL.” Read more…

Opposite Drug Prescription and Cost Trajectories following Integrative and Conventional Care for Pain – A Case-Control Study. Sundberg, Petzold M, Kohls N and Falkenberg T. PLoS ONE 2014; 9(5): e96717. doi:10.1371/journal.pone.0096717. “…Pharmacotherapy may have a limited role in long-term pain management. Comparative trajectories of drug prescriptions and costs, two quality-of-care indicators for pain conditions, are largely unknown subsequent to conventional or integrative care (IC) management. The objectives of this study were to compare prescribed defined daily doses (DDD) and cost of first line drugs for pain patients referred to conventional or anthroposophic IC in Stockholm County, Sweden … Conclusions: Drug prescriptions and costs of analgesics increased following conventional care and decreased following IC, indicating potentially fewer adverse drug events and beneficial societal cost savings with IC…”read more…

Sleep quality in pregnancy during treatment with Bryophyllum pinnatum: An observational study. Lambrigger-Steiner C, Simões-Wüst AP, Kuck A, Fürer K, Hamburgere M and von Mandach U. Phytomedicine 2014; 21: 753–757. http://dx.doi.org/10.1016/j.phymed.2013.11.003
“…In the present study, we investigated the sedativeeffect of Bryophyllum pinnatum, a phytotherapeutic medication used in anthroposophic medicine…Results: The number of wake-ups, as well as the subjective quality of sleep was significantly improved at the end of the treatment with B. pinnatum. The Epworth Sleeping Scale decreased, indicating a decrease of the tiredness during the day. There was, however, no evidence for prolongation of the sleep duration, reduction in the time to fall asleep, as well as change in the Fatigue Severity Scale after B. pinnatum. No serious adverse drug reactions were detected. Conclusion: B. pinnatum is a suitable treatment of sleep problems in pregnancy. The data of this study encourage further clinical investigations on the use of B. pinnatum in sleep disorders. …” read more…

Arts Therapies for Anxiety, Depression, and Quality of Life in Breast Cancer Patients: A Systematic Review and Meta-Analysis. Boehm K, Cramer H, Staroszynski T and Ostermann T: Hindawi Publishing Corporation. Evidence-Based Complementary and Alternative Medicine.Volume 2014, Article ID 103297, 9 pages http://dx.doi.org/10.1155/2014/103297 “…Our review indicates that arts interventions may have beneficial effects on anxiety in patients with breast cancer…”

Interaction of standardized mistletoe (Viscum album) extracts with chemotherapeutic drugs regarding cytostatic and cytotoxic effects in vitro. Weissenstein U , Kunz M , Urech K and Baumgartner S. BMC Complementary and Alternative Medicine 2014, 14 :6 Open access: http://www.biomedcentral.com/1472-6882/14/6
“...Our in vitro results suggest that no risk of safety by herb drug interactions has to be expected from the exposition of cancer cells to chemotherapeutic drugs and VAE simultaneously…”

Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients. Steele ML, Axtner J, Happe A, Kröz M, Matthes H and Schad F. Evidence-Based Complementary and Alternative Medicine Volume 2014, Article ID 724258, 11 pages http://dx.doi.org/10.1155/2014/724258
“…The results of this study indicate that mistletoe therapy is safe. ADRs were mostly mild to moderate in intensity and appear to be dose-related and explained by the immune-stimulating, pharmacological activity of mistletoe…”

Viscum album [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: A randomised clinical trial on overall survival. Tröger W, Galun M, Reif A et al. Eur J Cancer (2013) http://dx.doi.org/10.1016/j.ejca.2013.06.043
“…VaL therapy showed a significant and clinically relevant prolongation of OS. The study findings suggest VaL to be a non-toxic and effective second-line therapy that offers a prolongation of OS as well as less disease-related symptoms for patients with locally advanced or metastatic pancreatic cancer….”

NCCAM/NCI Phase 1 Study of Mistletoe Extract and Gemcitabine in Patients with Advanced Solid Tumors. Mansky PJ, Wallerstedt DB, Sannes TS et al. Evidence-Based Complementary and Alternative Medicine Volume 2013, Article ID 964592, http://dx.doi.org/10.1155/2013/964592
“…GEM plus mistletoe is well tolerated. No botanical/drug interactions were observed. Clinical response is similar to GEM alone…”

Network Oncology (NO) – a Clinical Cancer Register for Health Services Research and the Evaluation of Integrative Therapeutic Interventions in Anthroposophic Medicine. Schad F, Axtner J, Happe A, Breitkreuz T, Paxino C, Gutsch J, Matthes B, Debus M, Kröz M, Spahn G, Riess H, von Laue H and Matthes H. Forsch Komplementmed 2013;20:353–360 Published online: October 24, 2013 DOI: 10.1159/000356204 Accessible online at: www.karger.com/fok
“… Integrative oncological approaches attract a great number of patients visiting AM institutions. The NO provides an infrastructure to evaluate integrative interventions in AM, allows comparison to other clinical registers, and thus can contribute to health service research in this field…”

Intratumoral Mistletoe (Viscum album L) Therapy in Patients With Unresectable Pancreas Carcinoma - A Retrospective Analysis. Schad F, Axtner J, Buchwald D, Happe A, Popp S, Kröz M and Matthes H. Integr Cancer Ther 2013 DOI: 10.1177/1534735413513637) http://ict.sagepub.com/content/early/2013/12/18/1534735413513637
“…This retrospective analysis suggests that intratumoral-applicated mistletoe might contribute to improve survival of patients with pancreatic cancer. In conclusion, the application is feasible and safe, and its efficacy should be evaluated in a randomized controlled trial…”

Long-term outcomes of anthroposophic treatment for chronic disease: a four-year follow-up analysis of 1510 patients from a prospective observational study in routine outpatient settings. Hamre HJ, Kiene H, Glockmann A, Ziegler R, Kienle GS. BMC Res Notes 2013;6(269):doi:10.1186/1756-0500-6-269.

Anwendung von Cardiodoron® bei Patienten mit funktionellen Herz-Kreislauf-Beschwerden und/oder Schlafstörungen – Ergebnisse einer prospektiven, nichtinterventionellen Beobachtungsstudie. Claudia Rother,C. Forsch Komplementmed 2013;20:334–344 Published online: October 21, 2013 DOI: 10.1159/000355255 “…Administration of Cardiodoron® in Patients with Functional Cardiovascular Disorders and/or Sleep Disorders – Results of a Prospective, Non-Interventional Study: Cardiodoron shows positive effects in medical practice; it is a well-tolerated medicinal product for treatment of functional cardiovascular and/or sleep disorders with or without concomitant therapies…” Accessible online at: www.karger.com/fok


lisää tutkimustuloksia:

Katsaukset

  1. Klinische Forschung zur Anthroposophischen Medizin – Update eines «Health Technology Assessment»-Berichts und Status Quo. Kienle GS, Glockmann A, Grugel R, Hamre HJ, Helmut Keine H: Forsch Komplementmed 2011;18:4-4 (DOI: 10.1159/000331812).
  2. Influence of Viscum album L (European Mistletoe) Extracts on Quality of Life in Cancer Patients: A Systematic Review of Controlled Clinical Studies. Kienle GS and Kiene H. Integrative Cancer Therapies 2010:1-16.
  3. Clinical research in anthroposophic medicine. Hamre HJ, Kiene H, Kienle GS. Altern Ther Health Med 2009;15(6):52-55.
  4. Viscum album L. extracts in breast and gynaecological cancers: a systematic review of clinical and preclinical research. Kienle GS, Glockmann A, Schink M and Kiene H: Journal of Experimental & Clinical Cancer Research 2009;28:79.
  5. Survival of cancer patients treated with mistletoe extract (Iscador): a systematic literature review. Ostermann T, Raak C, Büssing A BMC Cancer 2009, 9:451 (pp. 1-9) (http://www.biomedcentral.com/1471-2407/9/451) read more... Comment on Mistletoe therapy in oncology (Cochrane Review 2008) IFAEMM: Kiene, Kienle 2008 read more...
  6. Complementary cancer therapy: a systematic review of prospective clinical trials on anthroposophic mistletoe extract. Kienle GS, Kiene H. Eur J Med Res 2007;12:103-19.
  7. Anthroposophic Medicine, Effectiveness, utility, costs, safety. Kienle GS, Kiene H, Albonico HU. . Schattauer, Stuttgart, New York, 2006.
  8. Mistletoe in cancer – a systematic review on controlled clinical trials. Kienle GS, Berrino F, Bussing A, Portalupi E, Rosenzweig S, Kiene H. Eur J Med Res 2003;8(3):109-19

Kliiniset tutkimukset

Allergiat

  1. Allergic disease and sensitization in Steiner school children. Floistrup H, et al. The Parsifal Study Group. J Allergy Clin Immunol. 2006 Jan;117(1):59-66. Epub 2005 Nov 28.
  2. Atopy in children of families with an anthroposophic lifestyle. Alm JS, Swartz J, Lilja G, Scheynius A, Pershagen G. Lancet. 1999 May 1;353(9163):1485-8. (1999)
  3. Allergic disease and sensitization in Steiner school children. Floistrup H, Swartz J, Bergstrom A, Alm JS, Scheynius A, van Hage M, Waser M, Braun-Fahrlander C, Schram-Bijkerk D, Huber M, et al. J Allergy Clin Immunol 2006;117(1):59-66.
  4. Bacterial and fungal agents in house dust and wheeze in children: the PARSIFAL study. Schram-Bijkerk D, Doekes G, Douwes J, Boeve M, Riedler J, Ublagger E, von Mutius E, Benz MR, Pershagen G, van Hage M, et al. Clin Exp Allergy 2005;35(10):1272-1278.
  5. Bacterial and fungal components in house dust of farm children, Rudolf Steiner school children and reference children--the PARSIFAL Study.Schram D, Doekes G, Boeve M, Douwes J, Riedler J, Ublagger E, von Mutius E, Budde J, Pershagen G, Nyberg F, et al. Allergy 2005;60(5):611-618.
  6. An anthroposophic lifestyle and intestinal microflora in infancy. Alm JS, Swartz J, Bjorksten B, Engstrand L, Engstrom J, Kuhn I, Lilja G, Mollby R, Norin, E, Pershagen G, Reinders C, Wreiber K, Scheynius A . Pediatr Allergy Immunol 2002;13(6) :402-11.

Astma ja hengistystie-infektiot

  1. Anthroposophic therapy for asthma: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Schnürer C, Glockmann A, Ziegler R, Willich SN, Kiene H.J Asthma Allergy 2009;2:111-28.
  2. Use and safety of anthroposophic medications for acute respiratory and ear infections: a prospective cohort study. Hamre HJ, Glockmann A, Fischer M, Riley D, Baars E, Kiene H. . Drug Target Insights 2007;2:209-19.

Krooniset sairaudet

  1. Anthroposophic therapies in chronic disease: the Anthroposophic Medicine Outcomes Study (AMOS) Hamre HJ, Becker-Witt C, Glockmann A, Ziegler R, Willich SN, Kiene H. Eur J Med Res. 2004 Jul 30;9(7):351-60. read more.
  2. Anthroposophic therapy for children with chronic disease: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Meinecke C, Glockmann A, Willich SN, Kiene H. BMC Pediatr 2009;9:39 read more
  3. Predictors of outcome after 6 and 12 months following anthroposophic therapy for adult outpatients with chronic disease: a secondary analysis from a prospective observational study. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Willich SN, Kiene H. BMC Research Notes 2010 Aug 3;3(218). read more
  4. Long-term outcomes of anthroposophic therapy for chronic low back pain: A two-year follow-up analysis. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Ziegler R, Willich SN, Kiene H. Journal of Pain Research 2009;2:75-85. read more
  5. Outcome of anthroposophic medication therapy in chronic disease: A 12-month prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Kienle GS, Willich SN, et al. Drug Design, Development and Therapy 2008;2:25-37.
  6. Anthroposophic vs. conventional therapy for chronic low back pain: a prospective comparative study. Hamre H, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Eur J Med Res 2007;12:302-10.
  7. Anthroposophic medical therapy in chronic disease: a four-year prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. BMC Complement Altern Med 2007;7(10):DOI 10.1186/1472-6882-7-10.

Kliininen onkologia

  1. Anthroposophic supportive treatment in children with medulloblastoma receiving first-line therapy. Seifert G, Rutkowski S, Jesse P, Madeleyn R, Reif M, Henze G and Längler A. J Pediatr Hematol Oncol 2011;33(3):105-10 read more...
  2. Anthroposophic Medicine in Paediatric Oncology in Germany: Results of a Population-Based Retrospective Parental Survey. Alfred Längler, Claudia Spix, Friedrich Edelhäuser, David D. Martin, Genn Kameda, Peter Kaatsch and Georg Seifert. Pediatr Blood Cancer 2010 DOI 10.1002/pbc. read more...
  3. Retrospective analysis of patients with advanced pancreatic cancer under palliative treatment and additive intratumoral application of viscum album l. F. Schad, D. Buchwald, A. Merkle, S. Popp, M. Kroez, H. Matthes: J Clin Oncol 29: 2011 (suppl; abstract e14538). online:http://abstract.asco.org/AbstView_102_82630.
  4. Evaluation of quality of life/life satisfaction in women with breast cancer in complementary and conventional care. Carlsson M, Arman M, Backman M, Flatters U, Hatschek T, Hamrin E. Acta Oncol. 2004;43(1):27-34.
  5. Influence of Viscum album L (European Mistletoe) Extracts on Quality of Life in Cancer Patients: A Systematic Review of Controlled Clinical Studies.Kienle GS and Kiene H. Integrative Cancer Therapies 2010:1-16.
  6. Molecular mistletoe therapy: friend or foe in established anti-tumor protocols? A multicenter, controlled, retrospective pharmaco-epidemiological study in pancreas cancer. Matthes H, Friedel WE, Bock PR, Zanker KS. Curr Mol Med 2010; 10: 430-9.read more...
  7. Durable tumour responses following primary high dose induction with mistletoe extracts: Two case reports. Orange M, Fonseca M, Lace A, vonLaue HB, Geider S. European Journal of Integrative Medicine 2010;2:63-69.read more...
  8. The influence of self- and autonomic regulation on cancer-related fatigue and distress in breast and colorectal cancer patients - A prospective study.Kröz M, Zerm R, Kuhnert N, Brauer D, Laue HBv, Bockelbrink A, Reif M, Schad F, Feder G, Heckmann C, Laue von S, Willich S, Girke M. European Journal of Integrative Medicine 2009;1(4):182. read more...
  9. Prospective controlled cohort studies on long-therapy of cervical cancer patients with a mistletoe preparation (Iscador). Grossarth-Maticek R, Ziegler R.. Forsch Komplementärmed 2007;14:140-7.
  10. A five-year follow-up of quality of life in women with breast cancer in anthroposophic and conventional care. Carlsson M, Arman M, Backman M, Flatters U, Hatschek T, Hamrin E. eCam 2006.
  11. Coping in women with breast cancer in complementary and conventional care over 5 years measured by the mental adjustment to cancer scale.Carlsson M, Arman M, Backman M, Hamrin E. J Altern Complement Med 2005;11(3):441-447.

Geriatria ja vahentuminen

  1. Usage of Complementary and Alternative Medicine Interventions by German Older Adults. Büssing A, Ostermann T, Heusser P, Matthiessen PF: J Altern Complement Med. 2011; 17(6):487-489
  2. Pharmacotherapy of elderly patients in everyday anthroposophic medical practice: a prospective, multicenter observational study. Jeschke E, Ostermann T, Vollmar HC, Tabali M, Kröz M, Bockelbrink A, Witt CM, Willich SN, Matthes H. BMC Geriatrics 2010, 10:48. read more...
  3. The self regulation questionnaire as a measure in quality of life research.Büssing A, Girke M, Heckmann C, Matthiesen P, Schad F, Ostermann T, Kröz M. Eur J Med Res 2009, 14(5):223-227. read more...

Neurologiset sairaudet ja migreeni

  1. Anthroposophic therapy for attention deficit hyperactivity: a two-year prospective study in outpatients. Harald J Hamre, Claudia M Witt, Gunver S Kienle, Christoph Meinecke, Anja Glockmann, Renatus Ziegler, Stefan N Willich, Helmut Kiene. International Journal of General Medicine 2010:3 239–253.
  2. Anthroposophic Therapy for Migraine: A Two-Year Prospective Cohort Study in Routine Outpatient Settings. Harald J. Hamre, Claudia M. Witt, Gunver S. Kienle, Anja Glockmann, Renatus Ziegler, Andreas Rivoir, Stefan N. Willich and Helmut Kiene. The Open Neurology Journal, 2010; Volume 4:100-110.

Psykiatria

  1. Course of life satisfaction in patients with depressive and addictive disorders after therapeutic intervention. Büssing A, Heusser P, Mundle G: International Journal of Social Psychiatry 2011; first published on March 25, 2011 as doi:10.1177/0020764010390498
  2. Anthroposophic therapy for anxiety disorders: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Ziegler R, Willich SN, Kiene H. Clinical Medicine: Psychiatry 2009;2:17-31 read more...

Gynekologia ja obstetriikka

  1. Effect of Bryophyllum pinnatum versus fenoterol on uterine contractility. Gwehenberger B, Rist L, Huch R, von Mandach U: Eur J Obstet Gynecol Reprod Biol 2004; 113(2):164-71.

Farmakovigilanssi, turvallisuus ja laadun valvonta

  1. Anthroposophic medicine in pediatric primary care: a prospective, multicenter observational study on prescribing patterns. Jeschke E, Ostermann T, Tabali M, Kroz M, Bockelbrink A, Witt CM, Willich SN, Matthes H: Altern Ther Health Med 2011;17:18-28.
  2. Pharmacotherapy of elderly patients in everyday anthroposophic medical practice: a prospective, multicenter observational study. Jeschke E, Ostermann T, Vollmar HC, Tabali M, Kröz M, Bockelbrink A, Witt CM, Willich SN, Matthes H. BMC Geriatrics 2010, 10:48. read more
  3. The treatment of children with anthroposophic medicine in daily primary care - Results of a network study. Jeschke E, Ostermann T, Tabali M, Bockelbrink A, Witt C, Willich S, Matthes H. European Journal of Integrative Medicine 2009;1(4):203. read more
  4. Prescribing practices in the treatment of upper respiratory tract infections in anthroposophic medicine. Jeschke E, Lueke C, Ostermann T, Tabali M, Huebner J, Matthes H. Forsch Komplementärmed 2007;14:207-15.
  5. QuaDoSta - ein frei konfigurierbares System zur Unterstützung multizentrischer Datenerhebungen in medizinischer Versorgung und Forschung. Jeschke E, Schad F, Pissarek J, Matthes B, Albrecht U, Matthes H. GMS Med Inform Biom Epidemiol 2007;3(2):Doc 10.
  6. Safety of homeopathic injectables for subcutaneous administration: a documentation of the experience of prescribing practitioners.Baars EW, Adriaansen-Tennekes R, Eikmans KJ. J Altern Complement Med 2005;11(4):609-616

Antroposofinen elämäntapa

  1. Allergic disease and sensitization in Steiner school children. Floistrup H, Swartz J, Bergstrom A, Alm JS, Scheynius A, van Hage M, Waser M, Braun-Fahrlander C, Schram-Bijkerk D, Huber M, et al. J Allergy Clin Immunol 2006;117(1):59-66.
  2. Bacterial and fungal agents in house dust and wheeze in children: the PARSIFAL study. Schram-Bijkerk D, Doekes G, Douwes J, Boeve M, Riedler J, Ublagger E, von Mutius E, Benz MR, Pershagen G, van Hage M, et al. Clin Exp Allergy 2005;35(10):1272-1278.
  3. Bacterial and fungal components in house dust of farm children, Rudolf Steiner school children and reference children--the PARSIFAL Study.Schram D, Doekes G, Boeve M, Douwes J, Riedler J, Ublagger E, von Mutius E, Budde J, Pershagen G, Nyberg F, et al. Allergy 2005;60(5):611-618.
  4. An anthroposophic lifestyle and intestinal microflora in infancy. Alm JS, Swartz J, Bjorksten B, Engstrand L, Engstrom J, Kuhn I, Lilja G, Mollby R, Norin, E, Pershagen G, Reinders C, Wreiber K, Scheynius A . Pediatr Allergy Immunol 2002;13(6) :402-11.
  5. Atopy in children of families with an anthroposophic lifestyle. Alm JS, Swartz j, Lilja G, Scheynius A, Pershagen G . Lancet 1999;353(9163) :1485-8.

Hoitoeurytmia

  1. Eurythmy Therapy in Anxiety. Schwab J, Murphy J, Andersson P, Lunde G, Kiene H, Hamre HJ, Kienle GS: Alternative Therapies in Health and Medicine 2011;17(4): 58-65. Read more
  2. Inner Correspondence and Peacefulness with Practices among Participants in Eurythmy Therapy and Yoga: A Validation Study. Büsssing A, Edelhäuser F, Weisskircher A, Fouladbakhsh JM and Heusser P. Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Volume 2011, Article ID 329023, 9 pages doi:10.1155/2011/329023 read more
  3. Therapeutic Eurythmy-movement therapy for children with attention deficit hyperactivity disorder (ADHD): a pilot study. Majorek M, Tuchelmann T, Heusser P. Complement Ther Nurs Midwifery 2004 10(1):46-53.
  4. Effects of complementary eurythmy therapy on heart rate variability. Seifert et al:, Complement Ther Med (2008), doi:10.1016/j.ctim.2008.09.005)
  5. Eurythmy therapy in chronic disease: a four-year propective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. BMC Public Health 2007;7(61):DOI 10.1186/1471-2458-7-61.

Ulkoiset hoidot, sairaanhoito, hieronnat

  1. Rhythmical massage therapy in chronic disease: a four-year prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. J Altern Complement Med 2007;13(6):635-42.
  2. Therkleson T, Sherwood P: Patient’s experience of the external therapeutic application of ginger by anthroposophically trained nurses. Indio-Pacific Journal of Phenomenology 2005;4:1-11.

Antroposofiset taideterapiat

  1. Anthroposophic art therapy in chronic disease: a four-year prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Explore 2007;3(4):365-71.
  2. Oscillations lf heart rate and respiration synchronize during poetry recitation. Cysarz D, von Bonin D, Lackner H, Heusser P, Moser M, Bettermann H: Am J Physiol Heart Circ Physiol 2004;287:H579-H58

Integratiivinen lääketiede

  1. Complementary Therapy Systems and Their Integrative Evaluation. Kienle GS, Albonico H-U, Fischer L, Frei-Erb M, Hamre HJ, Heusser P, Matthiessen PF, Renfer A, Kiene H. Journal of Science and Healing 2011(7/3): 175-187. read more (free download)
  2. Clinical judgement and the medical profession. Gunver S Kienle and Helmut Kiene. Journal of Evaluation in Clinical Practice 2010: doi:10.1111/j.1365-2753.2010.01560.x read more
  3. Mindfulness-Based Stress Reduction (MBSR) for integrative Cancer Care – A summary of evidence. Musial F, Büssing A, Heusser P, Kyung-Eun C, Ostermann T: Forschende Komplementärmedizin 2011; 18: (Online August 8, 2011; DOI: 10.1159/000330714)
  4. The challenges of complexity. Wolf U, Winkler M, Ephraim M, Hamre HJ, Lemann D: Primary Care 2011; 11(10):174-175.
  5. Professional treatment in the context of medical pluralism - A German perspective. Kiene H, Brinkhaus B, Fischer G, Girke M, Hahn EG, Hoppe HD, Jütte R, Kraft K, Klitzsch W, Matthiessen PF, Meister P, Michalsen A, Teut M, Willich SN, Heimpel H. Europaen Journal of Integrative Medicine 2010;2:53-56 read more
  6. A pilot study on the effects of a team building process on the perception of work environment in an integrative hospital for neurological rehabilitation. Ostermann T, Bertram M, Büssing A BMC Complementary and Alternative Medicine 2010; 10, 10 (http://www.biomedcentral.com/1472-6882/10/10: 25-44) (pp. 1-10) read more
  7. An integrative approach of cancer treatment with mistletoe therapy, surgery, irradiation and chemotherapy in CAM settings. Schad F, Merkle A, Hoffmann G, Lenneweit G, Spahn G, Hesse M, Paxino C, Wellmann G, Matthes B, Baute R, Breitkreuz T, Matthes H. European Journal of Integrative Medicine 2009;1(4):184. read more
  8. Integrative medical education: Educational strategies and preliminary evaluation of the Integrated Curriculum for Anthroposophic Medicine (ICURAM). Scheffer C, et al. Patient Educ Couns (2012), read more
  9. Medicinal Systems of Complementary and Alternative Medicine: A Cross-Sectional Survey at a Pediatric Emergency Department. Zuzak J, Zuzak-Siegrist I, Rist L, Staubli G, Simoñes-Wüst AP. The Journal of Alternative and Complementary Medicine, Volume 16, Number 4, 2010, pp. 473-479.
  10. Anthroposophic perspectives in primary care. Cantor IS, Rosenzweig S, Volume 24, Number 4, December 1997.

Study Results in Anthroposophic Medicine

Forschungsinstitut Havelhöhe, Berlin: www.fih-berlin.de/html/publikationen.html

Lehrstuhl für Medizintheorie, Integrative und Anthroposophische Medizin, Witten/Herdecke: www.uni-wh.de/gesundheit/lehrstuhl-medizintheorie/forschung/

Institute for Applied Epistemology and Medical Methodology at the University of Witten/Herdecke, Freiburg: www.ifaemm.de/F5_publi.htm


Lisätietoja:

Suomen Antroposofisen Lääketieteen Lääkäriyhdistys ry SALLY, www.antroposofinenlaaketiede.fi

International Federation of Anthroposophic Medical Associations IVAA, www.ivaa.info

Vapa hengentieteellinen korkeakoulu, Lääketieteellinen osasto, Goetheanum, Dornach, Sveitsi www.medsektion-goetheanum.org